Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335244 | 0.89 | MAPT (0.41) | PIN1HDAC1ACP1ABL1FABP6 | |
| SCHEMBL335890 | 0.85 | ACP1 (0.40) | PIN1HDAC1ACP1ABL1FABP6 | |
| SCHEMBL15282285 | 0.85 | ACP1 (0.46) | ACP1ABL1FABP6MAPTRAB9A | |
| SCHEMBL15282212 | 0.85 | ACP1 (0.46) | ACP1ABL1FABP6MAPTRAB9A | |
| SCHEMBL334912 | 0.84 | F7 (0.40) | PIN1HDAC1ACP1ABL1FABP6 | |
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | ACP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL335351 | 0.84 | EGFR (0.50) | HDAC1ACP1APPABL1FABP6 | |
| SCHEMBL335390 | 0.84 | ABL1 (0.44) | PIN1ACP1ABL1FABP6MAPT | |
| SCHEMBL335694 | 0.84 | SMN1; SMN2 (0.39) | PIN1HDAC1ACP1ABL1FABP6 | |
| SCHEMBL336367 | 0.84 | MAPT (0.47) | ACP1ABL1FABP6MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |