Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | SMN1; SMN2ALDH1A1HPGDLMNAACP1 | |
| SCHEMBL335570 | 0.84 | PIN1 (0.47) | ACP1PIN1RAB9AMAPTABL1 | |
| SCHEMBL15282212 | 0.83 | ACP1 (0.46) | SMN1; SMN2ALDH1A1HPGDLMNAACP1 | |
| SCHEMBL15282285 | 0.83 | ACP1 (0.46) | SMN1; SMN2ALDH1A1HPGDLMNAACP1 | |
| SCHEMBL335582 | 0.82 | TNIK (0.42) | SMN1; SMN2ALDH1A1HPGDACP1RAB9A | |
| SCHEMBL336031 | 0.82 | ABL1 (0.41) | SMN1; SMN2ALDH1A1HPGDLMNAACP1 | |
| SCHEMBL335244 | 0.82 | MAPT (0.41) | SMN1; SMN2ALDH1A1HPGDACP1PIN1 | |
| SCHEMBL336367 | 0.82 | MAPT (0.47) | SMN1; SMN2ALDH1A1LMNAACP1RAB9A | |
| SCHEMBL335141 | 0.81 | ABL1 (0.40) | SMN1; SMN2ALDH1A1LMNAACP1RAB9A | |
| SCHEMBL335948 | 0.81 | ABL1 (0.45) | SMN1; SMN2ALDH1A1LMNAACP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |