Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334912 | 0.87 | F7 (0.40) | ACP1TYMSF7F9RAB9A | |
| SCHEMBL8219489 | 0.85 | F9 (0.43) | ACP1TYMSF7F9RAB9A | |
| SCHEMBL335570 | 0.85 | PIN1 (0.47) | ACP1RAB9AMAPTABL1FABP6 | |
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | ACP1TYMSF7RAB9AMAPT | |
| SCHEMBL335244 | 0.83 | MAPT (0.41) | ACP1RAB9AMAPTNPC1ABL1 | |
| SCHEMBL15282285 | 0.83 | ACP1 (0.46) | ACP1F7RAB9AMAPTNPC1 | |
| SCHEMBL15282212 | 0.83 | ACP1 (0.46) | ACP1F7RAB9AMAPTNPC1 | |
| SCHEMBL336367 | 0.82 | MAPT (0.47) | ACP1TYMSF7F9RAB9A | |
| SCHEMBL335878 | 0.81 | ABL1 (0.43) | ACP1TYMSF7F9MAPT | |
| SCHEMBL335948 | 0.81 | ABL1 (0.45) | ACP1F7F9RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |