Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | ATF4 | P18848 | 4/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355773 | 0.84 | MCHR1 (0.37) | HRH4HRH3MCHR1DRD2ATF4 | |
| SCHEMBL3432233 | 0.79 | GRIN1 (0.46) | HRH4HRH3MCHR1DRD2TP53 | |
| SCHEMBL3355534 | 0.76 | MCHR1 (0.40) | HRH4HRH3MCHR1DRD2ATF4 | |
| SCHEMBL3359475 | 0.76 | DRD2 (0.34) | HRH4HRH3MCHR1DRD2ATF4 | |
| SCHEMBL3354315 | 0.72 | ATF4 (0.34) | MCHR1DRD2ATF4ADAMTS5 | |
| SCHEMBL3355866 | 0.69 | MCHR1 (0.34) | HRH4HRH3MCHR1DRD2ATF4 | |
| SCHEMBL3355002 | 0.67 | CCR1 (0.54) | — | |
| SCHEMBL3355449 | 0.67 | CCR1 (0.54) | — | |
| SCHEMBL3359150 | 0.67 | ADAMTS5 (0.40) | ATF4ADAMTS5 | |
| SCHEMBL3353721 | 0.67 | DRD4 (0.39) | MCHR1ATF4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | CCR1, CCR4, CCR5 | HRH4 224/4885HRH3 307/4885MCHR1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.