Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738493 | 0.89 | MTNR1A (0.40) | MTNR1AMTNR1BTSHRUSP2ALOX15 | |
| SCHEMBL10354336 | 0.77 | MTNR1A (0.73) | MTNR1AMTNR1BTSHRUSP2ALOX15 | |
| SCHEMBL10826205 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BTSHRMAPK1PKM | |
| Sulfuric Acid SCHEMBL11083725 | 0.74 | PKM (0.47) | MTNR1AMTNR1BTSHRMAPK1PKM | |
| SCHEMBL27890220 | 0.73 | KDM4E (0.44) | MTNR1AMTNR1BTSHRMAPK1HSD17B10 | |
| SCHEMBL33691 | 0.73 | MAPT (0.39) | TSHRALOX15MAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5718659 | 0.73 | NR4A1 (0.36) | TSHRMAPK1L3MBTL1CYP2C19ALDH1A1 | |
| Sulfuric Acid SCHEMBL27584470 | 0.71 | RAPGEF4 (0.42) | TSHRHSD17B10L3MBTL1PKMCYP2C19 | |
| SCHEMBL1979097 | 0.71 | CYP3A4 (0.37) | TSHRALOX15MAPK1HSD17B10L3MBTL1 | |
| SCHEMBL8445226 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BTSHRPKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| EP-3638200-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'Oreal (FR) | 2020-04-22 | — | — | EP | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | claimed |
| EP-0850636-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2013-11-20 | — | — | EP | claimed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| EP-0850637-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2010-11-10 | — | — | EP | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| US-6152967-A | COMPOSITION FOR HAIR DYEING COMPRISING AT LEAST ONE OXIDATION BASE AND BILIRUBIN OXIDASE | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-6099590-A | READY-TO-USE COMPOSITION COMPRISING OXIDATION BASE(S), CHOLINE OXIDASE(S), AND DONOR(S) FOR THE CHOLINE OXIDASE; MULTICOMPARTMENT DYE KITS; PROCESS FOR DYEING; STRONGER COLORATIONS | L'OREAL (FR) | 2000-08-08 | — | — | US | claimed |
| US-6090159-A | READY-TO-USE OXIDATION DYEING COMPOSITION COMPRISING AN OXIDATION BASE, SARCOSINE OXIDASE AS OXIDIZER, AND AT LEAST ONE DONOR FOR THE ENZYME; STRONGER COLORATION, NO BLEACHING | L'OREAL (FR) | 2000-07-18 | — | — | US | claimed |
| US-6001135-A | READY-TO-USE OXIDATION DYEING FOR HUMAN HAIR | L'OREAL (FR) | 1999-12-14 | — | — | US | claimed |
| US-5993490-A | Composition for the oxidation dyeing of keratin fibers containing a cationic direct dye and dyeing process using this composition | L'OREAL (FR) | 1999-11-30 | — | — | US | claimed |
| EP-0850638-B1 | Oxidative dye composition for keratinic fibres and dyeing process using this composition | OREAL (FR) | 1999-09-01 | — | — | EP | claimed |
| US-5919273-A | READY-TO-USE COMPOSITION DYES HAIR GIVING UNIFORM COLOR; OXIDATION BASE IN COMBINATION WITH A SUBSTITUTED META-AMINOPHENOL COUPLER, CATIONIC DIRECT DYE AND OXIDIZING AGENT; MULTICOMPARTMENT DYE KIT | L'OREAL (FR) | 1999-07-06 | — | — | US | claimed |
| EP-0850637-B1 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 1999-06-02 | — | — | EP | claimed |
| EP-0850636-B1 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 1999-05-06 | — | — | EP | claimed |
| EP-0852135-B1 | Oxidative dyeing composition for keratin fibres and dyeing method employing it | OREAL (FR) | 1999-04-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | KRT18, ALK, AOC1 | MTNR1A 4641/4885MTNR1B 4572/4885TSHR 4714/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | MTNR1A 4324/4885MTNR1B 4490/4885TSHR 4844/4885 |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | KRT18, ALK, AOC1 | MTNR1A 4465/4885MTNR1B 4311/4885TSHR 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.