Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335141 | 0.88 | ABL1 (0.40) | RAB9ASMN1; SMN2LMNAABL1FABP6 | |
| SCHEMBL334912 | 0.88 | F7 (0.40) | RAB9ASMN1; SMN2ABL1FABP6F7 | |
| SCHEMBL335501 | 0.87 | NPC1 (0.43) | RAB9ASMN1; SMN2ABL1FABP6F7 | |
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | RAB9ATP53SMN1; SMN2LMNAABL1 | |
| SCHEMBL336031 | 0.84 | ABL1 (0.41) | RAB9ATP53SMN1; SMN2LMNAABL1 | |
| SCHEMBL336367 | 0.84 | MAPT (0.47) | RAB9ASMN1; SMN2LMNAABL1FABP6 | |
| SCHEMBL336014 | 0.84 | ABL1 (0.41) | SMN1; SMN2ABL1FABP6F7F9 | |
| SCHEMBL335878 | 0.83 | ABL1 (0.43) | SMN1; SMN2LMNAABL1FABP6F7 | |
| SCHEMBL335948 | 0.83 | ABL1 (0.45) | RAB9ASMN1; SMN2LMNAABL1FABP6 | |
| SCHEMBL335373 | 0.83 | TYMS (0.43) | ABL1FABP6F7F9ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |