Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853004 | 0.96 | ALOX5 (0.57) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL10068940 | 0.86 | TRPA1 (0.56) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL22539594 | 0.85 | EGFR (0.58) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL29035128 | 0.84 | CNR2 (0.60) | ALOX5TP53MEN1NPC1RAB9A | |
| SCHEMBL31027246 | 0.84 | BACE1 (0.62) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL4280343 | 0.84 | BACE1 (0.62) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL31027234 | 0.83 | BACE1 (0.60) | ALOX5BACE1TP53MEN1NPC1 | |
| Methane SCHEMBL28999758 | 0.83 | BACE1 (0.60) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL29538733 | 0.82 | BACE1 (0.59) | ALOX5BACE1TP53MEN1NPC1 | |
| SCHEMBL27754273 | 0.82 | HPGD (0.57) | ALOX5BACE1TP53MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503480-B2 | Cyclic phosphazene compound having oxaphosphorin ring-containing structure | FUSHIMI PHARMACEUTICAL CO., LTD. (JP) | 2025-12-23 | — | — | US | disclosed |
| US-20230339994-A1 | CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE | FUSHIMI PHARMACEUTICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-11708530-B2 | Organic ligands for templatable mesoscale nanocapsules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-25 | — | — | US | disclosed |
| EP-4202013-A1 | CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE | Fushimi Pharmaceutical Co., Ltd. (JP) | 2023-06-28 | — | — | EP | disclosed |
| EP-4021431-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | Vestlandets Innovasjonsselskap AS (NO) | 2022-07-06 | — | — | EP | disclosed |
| WO-2022019021-A1 | CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE | 株式会社伏見製薬所 | 2022-01-27 | — | — | WO | disclosed |
| US-20170145011-A1 | Pyrrolopyrazine-Spirocyclic piperidine amides as modulators of ion channels | VERTEX PHARMA (US) | 2017-05-25 | — | — | US | disclosed |
| US-9511067-B2 | Substituted spiro[piperidine-4,1'-pyrrolo[1,2-a]pyrazine]s as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150174127-A1 | Pyrrolopyrazine-Spirocyclic piperidine amides as modulators of ion channels | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2015-06-25 | — | — | US | disclosed |
| US-8916565-B2 | Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-12-23 | — | — | US | disclosed |
| US-20070179304-A1 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-08-02 | — | — | US | disclosed |
| CN-1920666-A | Photosensitive slurry | SUMITOMO CHEMICAL CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| WO-2006117609-A2 | PHENOXYPROPYLPIPERIDINES AND -PYRROLIDINES AND THEIR USE AS HISTAMINE H3 -RECEPTOR LIGANDS | BIOPROJET (FR) | 2006-11-09 | — | — | WO | disclosed |
| EP-1710239-A1 | PROCESS FOR PRODUCING CHROMAN COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-10-11 | — | — | EP | disclosed |
| CN-1071110-C | Antibacterial antiplaque, anticalculus oral composition | COLGATE PALMOLIVE CO (US) | 2001-09-19 | — | — | CN | disclosed |
| CN-1045533-C | Continuous process for making a non-newtonian paste or cream like material | COLGATE PALMOLIVE CO (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1083700-A | Make the continuation method of non newtonian type cream, white shape goods | COLGATE PALMOLIVE CO (US) | 1994-03-16 | — | — | CN | disclosed |
| CN-1066070-A | Promote the new benzo-fused lactams that tethelin discharges | MERCK & CO INC (US) | 1992-11-11 | — | — | CN | disclosed |
| CN-1049606-A | Antibacterium, antibiotic dental plaque, anti-calculus oral cavity composition | COLGATE PALMOLIVE CO (US) | 1991-03-06 | — | — | CN | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174127-A1 | Pyrrolopyrazine-Spirocyclic piperidine amides as modulators of ion channels | KCNJ2, KCNJ5, KCNJ1 | ALOX5 2415/4885BACE1 3722/4885TP53 4003/4885 |
| US-20170145011-A1 | Pyrrolopyrazine-Spirocyclic piperidine amides as modulators of ion channels | KCNJ2, KCNJ5, KCNJ1 | ALOX5 2415/4885BACE1 3722/4885TP53 4003/4885 |
| US-20230339994-A1 | CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE | PFAS, PHOSPHO1, PAF1 | ALOX5 817/4885BACE1 1578/4885TP53 2697/4885 |
| US-11708530-B2 | Organic ligands for templatable mesoscale nanocapsules | EPCAM, L1CAM, ICOSLG | ALOX5 1793/4885BACE1 4594/4885TP53 502/4885 |
| US-12503480-B2 | Cyclic phosphazene compound having oxaphosphorin ring-containing structure | PFAS, PHOSPHO1, PAF1 | ALOX5 817/4885BACE1 1578/4885TP53 2697/4885 |
| US-20070179304-A1 | Process for producing chroman compound | TAF9, TAF1, CHD1 | ALOX5 224/4885BACE1 2059/4885TP53 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.