Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712372 | 0.83 | HTR2A (0.37) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| SCHEMBL9243164 | 0.79 | NQO1 (0.58) | TSHRKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9363954 | 0.79 | NFE2L2 (0.39) | CYP1A2TSHRMAOBMAOAMEN1 | |
| SCHEMBL100407 | 0.78 | LTA4H (0.41) | TSHR | |
| SCHEMBL23581930 | 0.76 | CHRNB2 (0.41) | CYP1A2CYP3A4HPGDNPC1RAB9A | |
| SCHEMBL16179196 | 0.73 | KCNH2 (0.43) | CYP1A2CYP3A4MEN1KMT2AKCNH2 | |
| SCHEMBL10735235 | 0.73 | TDP1 (0.45) | CYP1A2TSHRMEN1KMT2ALMNA | |
| SCHEMBL10887507 | 0.72 | IDO1 (0.45) | PPARAMAOBMAOAPPARGKCNH2 | |
| SCHEMBL10724096 | 0.72 | BCL9 (0.51) | CYP3A4TSHRMAOBMEN1KMT2A | |
| SCHEMBL3225876 | 0.71 | ALDH1A1 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455367-A | CYAN COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-19 | — | — | US | claimed |
| US-4454225-A | COUPLERS PREVENTING YELLOW IDSCOLORATION AT UNEXPOSED AREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-12 | — | — | US | claimed |
| US-4334011-A | CYAN DYE FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-08 | — | — | US | claimed |
| US-8871794-B2 | Small-molecule agonists for type-2 orexin receptor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140051700-A1 | Small-molecule agonists for type-2 orexin receptor | UNIVERSITY OF TEXAS, BOARD OF REGENTS | 2014-02-20 | — | — | US | disclosed |
| US-8258163-B2 | Small-molecule agonists for type-2 orexin receptor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-09-04 | — | — | US | disclosed |
| US-20100150840-A1 | Small-molecule agonists for type-2 orexin receptor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-06-17 | — | — | US | disclosed |
| US-4639447-A | Azolylnitriles, and fungicides containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0164088-A2 | Azolyl nitriles and fungicides containing them | BASF Aktiengesellschaft (DE) | 1985-12-11 | — | — | EP | disclosed |
| EP-0129798-A1 | Fungicidal azole compounds, their preparation and use | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | disclosed |
| US-4455367-A | CYAN COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |
| US-4454225-A | COUPLERS PREVENTING YELLOW IDSCOLORATION AT UNEXPOSED AREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4334011-A | CYAN DYE FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100150840-A1 | Small-molecule agonists for type-2 orexin receptor | HCRTR2, HCRTR1, OXTR | ALOX5 1063/4885PPARA 494/4885CYP1A2 647/4885 |
| US-20140051700-A1 | Small-molecule agonists for type-2 orexin receptor | HCRTR2, HCRTR1, OXTR | ALOX5 1063/4885PPARA 494/4885CYP1A2 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.