Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697075 | 0.89 | CYP19A1 (0.38) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL8538439 | 0.85 | CYP19A1 (0.35) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL8542953 | 0.83 | PGR (0.42) | CYP19A1 | |
| SCHEMBL9948623 | 0.81 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL3356889 | 0.80 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL6301569 | 0.80 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL4945163 | 0.80 | SHBG (0.48) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9947828 | 0.78 | CYP19A1 (0.42) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9948721 | 0.77 | CYP19A1 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL8370954 | 0.77 | CYP19A1 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404283-A2 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-12-27 | — | — | EP | disclosed |