Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.44 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356042 | 0.92 | CACNB4 (0.52) | CTSBALDH1A1LMNASMN1; SMN2CACNB4 | |
| SCHEMBL3354509 | 0.91 | CACNB4 (0.54) | CTSBALDH1A1LMNASMN1; SMN2CACNB4 | |
| SCHEMBL3351079 | 0.91 | HTR6 (0.48) | CTSBMAPTALDH1A1SMN1; SMN2CACNB4 | |
| SCHEMBL3357652 | 0.85 | CTSB (0.59) | CTSBKCNJ1MAPTALDH1A1LMNA | |
| SCHEMBL3353615 | 0.81 | HRH3 (0.41) | MAPTKMT2AMTNR1BCNR1CNR2 | |
| SCHEMBL13537524 | 0.81 | HRH3 (0.41) | ALDH1A1KMT2AMTNR1BPOLBCNR1 | |
| SCHEMBL3357604 | 0.80 | CTSB (0.56) | CTSBKCNJ1MAPTALDH1A1LMNA | |
| SCHEMBL3352610 | 0.79 | F2RL3 (0.39) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3352715 | 0.79 | HTR7 (0.59) | CTSBALDH1A1LMNACACNB4CACNA1A | |
| SCHEMBL3358883 | 0.78 | CTSB (0.59) | CTSBKCNJ1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |