Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357630 | 0.90 | ALDH1A1 (0.53) | HTR6HTR7LMNACDK2SMN1; SMN2 | |
| SCHEMBL3353450 | 0.90 | HTR6 (0.62) | HTR6HTR7CDK1CCNB1LMNA | |
| SCHEMBL3357652 | 0.88 | CTSB (0.59) | HTR6LMNASMN1; SMN2CTSB | |
| SCHEMBL3352715 | 0.84 | HTR7 (0.59) | HTR6HTR7CDK1CCNB1LMNA | |
| SCHEMBL3351079 | 0.83 | HTR6 (0.48) | HTR6HTR7CDK1CCNB1SMN1; SMN2 | |
| SCHEMBL3352978 | 0.81 | CACNB4 (0.56) | HTR6LMNACDK2SMN1; SMN2CTSB | |
| SCHEMBL2075237 | 0.80 | HRH3 (0.53) | HTR7LMNACDK2SMN1; SMN2 | |
| SCHEMBL3356257 | 0.80 | CACNB4 (0.58) | HTR6LMNACDK2SMN1; SMN2CTSB | |
| SCHEMBL3351522 | 0.79 | HTR6 (0.51) | HTR6HTR7LMNACDK2SMN1; SMN2 | |
| SCHEMBL3358883 | 0.78 | CTSB (0.59) | HTR6LMNASMN1; SMN2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |