Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343377 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL246198 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9870423 | 0.74 | AKR1B1 (0.42) | ALDH1A1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL10606249 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL7833003 | 0.73 | MAOA (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11271210 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| Acetic Acid SCHEMBL343375 | 0.70 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL343281 | 0.70 | KEAP1 (0.53) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11217585 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL343740 | 0.70 | MAOA (0.47) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666770-A1 | Process for obtaining olopatadine and intermediates | Crystal Pharma S.A.U (ES) | 2013-11-27 | — | — | EP | disclosed |
| EP-2145882-B1 | Process for obtaining olopatadine and intermediates | CRYSTAL PHARMA SAU (ES) | 2013-08-21 | — | — | EP | disclosed |
| EP-2145882-A1 | Process for obtaining olopatadine and intermediates | Ragactives, S.L.U. (ES) | 2010-01-20 | — | — | EP | disclosed |