SCHEMBL3360163

SCHEMBL3360163

CCCCC(CC)COc1ccc(-c2nc(-c3ccc(OCC(CC)CCCC)c(C)c3O)nc(-c3c(C)n(CC(CC)CCCC)c4ccccc34)n2)c(O)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.33
HPGD P15428 4/20 0.33
LMNA P02545 4/20 0.33
MAPT P10636 3/20 0.33
CYP3A4 P08684 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 5/20 0.32
CA2 P00918 1/20 0.32
GAA P10253 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.32
XBP1 P17861 1/20 0.32
PPARG P37231 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360827 0.89 KDM4E (0.35) KDM4EMAPTMEN1KMT2AHSD17B10
SCHEMBL3360359 0.88 KDM4E (0.34) KDM4EHPGDLMNAMAPTMEN1
SCHEMBL3361773 0.84 CA2 (0.33) LMNAMAPTCYP3A4MEN1KMT2A
SCHEMBL3363710 0.82 ALDH1A1 (0.37) LMNACYP3A4ALDH1A1CA2
SCHEMBL3360185 0.80 PRSS1 (0.33) LMNAMAPTCYP3A4ALDH1A1CA2
SCHEMBL3469122 0.79 PDE10A (0.33) LMNACYP3A4ALDH1A1CA2MAPK1
SCHEMBL3469062 0.79 LMNA (0.32) LMNACYP3A4ALDH1A1CA2HSD17B10
SCHEMBL3468866 0.78 DYRK1A (0.35) LMNAMAPTCYP3A4ALDH1A1CA2
SCHEMBL3364964 0.77 ICMT (0.33) PPARGCNR2CNR1
SCHEMBL3360821 0.77 KDM4E (0.38) KDM4EMAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP claimed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO claimed
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed