Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168647 | 0.80 | PTPN1 (0.39) | HMGCRCA1CA2TDP1PTPN1 | |
| SCHEMBL1260575 | 0.79 | HMGCR (0.41) | HMGCRCA1CA2PKMCA12 | |
| SCHEMBL9053891 | 0.78 | TDP1 (0.42) | PKMMAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL2214596 | 0.78 | MAPT (0.36) | HMGCRCA1CA12CA7CA9 | |
| SCHEMBL5746585 | 0.77 | ALOX5 (0.52) | PTGS2ALOX5 | |
| SCHEMBL2213832 | 0.76 | PKM (0.38) | HMGCRCA1CA2PKMCA12 | |
| SCHEMBL5749454 | 0.75 | ALOX5 (0.42) | CA1CA2PKMCA12CA3 | |
| SCHEMBL32666071 | 0.72 | HSD17B2 (0.48) | CA1CA2PKMCA12CA3 | |
| SCHEMBL11454709 | 0.70 | KMT2A (0.37) | MAPT | |
| SCHEMBL4551834 | 0.70 | PKM (0.54) | HMGCRPKMMAPTTDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| CN-105377225-A | Uv compositions having low active concentrations and high in vivo spf | PROCTER & GAMBLE | 2016-03-02 | — | — | CN | disclosed |
| EP-2198837-B1 | Cosmetic composition containing four surfactants, a cationic polymer and a zinc salt | ORÉAL L (FR) | 2016-02-17 | — | — | EP | disclosed |
| WO-2015140472-A1 | COSMETIC COMPOSITION COMPRISING BENEFICIAL AGENTS FOR KERATIN MATERIALS, AND A MIXTURE OF SULFONATE-CONTAINING DERIVATIVES OF OLEFINS, AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2015-09-24 | — | — | WO | disclosed |
| EP-2198837-A1 | Cosmetic composition containing four surfactants, a cationic polymer and a zinc salt | L'OREAL (FR) | 2010-06-23 | — | — | EP | disclosed |