Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364042 | 0.89 | DPP4 (0.44) | ABCB1MAPTALDH1A1HPGDGAA | |
| SCHEMBL3363284 | 0.87 | DPP4 (0.41) | ABCB1MAPTALDH1A1HPGDGAA | |
| SCHEMBL7721777 | 0.81 | MAPT (0.40) | MAPTALDH1A1HPGDGAALMNA | |
| Hydrochloric Acid SCHEMBL3365128 | 0.80 | DPP4 (0.50) | MAPTALDH1A1HPGDGAADPP4 | |
| SCHEMBL3362011 | 0.79 | DPP4 (0.40) | ABCB1ALDH1A1DPP4TSHRKMT2A | |
| SCHEMBL3360962 | 0.79 | DPP4 (0.41) | ABCB1ALDH1A1GAADPP4KMT2A | |
| SCHEMBL3362437 | 0.78 | DPP4 (0.45) | ABCB1ALDH1A1DPP4TSHRDYRK1A | |
| SCHEMBL3363099 | 0.77 | DPP4 (0.49) | ABCB1ALDH1A1GAADPP4LMNA | |
| SCHEMBL3362101 | 0.76 | DPP4 (0.67) | MAPTALDH1A1HPGDGAADPP4 | |
| SCHEMBL3361815 | 0.76 | LMNA (0.46) | ABCB1MAPTHPGDGAADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |