SCHEMBL3363037

SCHEMBL3363037

Cc1c(F)ccc2cc(O)c(=O)[nH]c12

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 18/20 0.61
DDO Q99489 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363264 0.80 DAO (0.61) DAODDO
SCHEMBL3360987 0.80 DAO (0.61) DAODDO
SCHEMBL3424009 0.80 DAO (0.57) DAODDO
SCHEMBL3432869 0.78 DAO (0.58) DAODDO
SCHEMBL3362300 0.76 DAO (1.00) DAODDO
SCHEMBL3432805 0.73 DAO (0.67) DAODDO
SCHEMBL3599395 0.73 EIF4A3 (0.57) DAO
SCHEMBL3435254 0.73 DAO (0.61) DAODDO
SCHEMBL3424908 0.73 DAO (0.53) DAODDO
SCHEMBL3362656 0.73 DAO (0.61) DAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058314-A1 HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF PFIZER INC. (US) 2010-05-27 WO claimed
WO-2010058314-A1 HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF PFIZER INC. (US) 2010-05-27 WO disclosed