Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 11/20 | 0.60 |
| ▸ | DDO | Q99489 | 5/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360786 | 0.77 | DAO (0.58) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL16767853 | 0.75 | DAO (1.00) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3422795 | 0.75 | DAO (0.62) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3431869 | 0.74 | DAO (0.49) | DAODDOSRC | |
| SCHEMBL22394978 | 0.74 | EIF4A3 (0.51) | GRIN1 | |
| SCHEMBL29425148 | 0.74 | EIF4A3 (0.51) | GRIN1 | |
| SCHEMBL9387604 | 0.73 | DAO (0.55) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL29301780 | 0.72 | GRIN1 (0.35) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL26262529 | 0.72 | MEN1 (0.36) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL8873562 | 0.71 | DAO (0.51) | DAODDOGRIN1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |