Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 14/20 | 0.62 |
| ▸ | DDO | Q99489 | 6/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361286 | 0.79 | DAO (0.60) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3420670 | 0.79 | DAO (0.64) | DAODDO | |
| SCHEMBL16767845 | 0.77 | DAO (1.00) | DAODDO | |
| SCHEMBL3363146 | 0.75 | DAO (0.60) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3420415 | 0.74 | PGR (0.39) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3424009 | 0.73 | DAO (0.57) | DAODDO | |
| SCHEMBL3421760 | 0.71 | DAO (0.55) | DAODDO | |
| SCHEMBL9389927 | 0.69 | DAO (0.49) | DAODDOGRIN1GRIN2DGRIN3B | |
| SCHEMBL3361624 | 0.68 | DAO (0.58) | DAODDO | |
| SCHEMBL19779945 | 0.67 | GRIN1 (0.47) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |