Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.49 |
| ▸ | DDO | Q99489 | 5/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872831 | 0.78 | CA12 (0.41) | SRCMCL1ARPGR | |
| SCHEMBL3359175 | 0.77 | DAO (0.64) | DAODDOAR | |
| SCHEMBL3360786 | 0.77 | DAO (0.58) | DAODDOSRC | |
| SCHEMBL3363146 | 0.74 | DAO (0.60) | DAODDOSRC | |
| SCHEMBL4706825 | 0.73 | GRIN1 (0.47) | DAODDO | |
| SCHEMBL8873562 | 0.71 | DAO (0.51) | DAODDOSRC | |
| SCHEMBL3419432 | 0.71 | DAO (0.51) | DAODDOMCL1ARPGR | |
| SCHEMBL9007832 | 0.70 | DAO (0.65) | DAODDOPARP1 | |
| SCHEMBL6679449 | 0.70 | AR (0.64) | ARPGR | |
| SCHEMBL3363859 | 0.69 | DAO (0.57) | DAODDOSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |