Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 14/20 | 0.58 |
| ▸ | DDO | Q99489 | 6/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420670 | 0.84 | DAO (0.64) | DAODDOHRH4 | |
| SCHEMBL22198970 | 0.79 | HRH4 (0.45) | DAODDOHRH4 | |
| SCHEMBL3421507 | 0.79 | DAO (0.58) | DAODDOHRH4 | |
| SCHEMBL3434396 | 0.79 | DAO (0.47) | DAODDO | |
| SCHEMBL3363264 | 0.78 | DAO (0.61) | DAODDO | |
| SCHEMBL18171730 | 0.77 | HRH4 (0.43) | DAODDOHRH4 | |
| SCHEMBL22185228 | 0.77 | HRH4 (0.43) | DAOHRH4 | |
| SCHEMBL21549766 | 0.76 | IDH1 (0.49) | DAODDOHRH4 | |
| SCHEMBL18744798 | 0.76 | HRH4 (0.40) | DAODDOHRH4 | |
| SCHEMBL3395947 | 0.76 | DAO (0.47) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |