Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TKT | P29401 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPP5C | P53041 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2949884 | 0.81 | TKT (0.69) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| SCHEMBL13741567 | 0.80 | TKT (0.68) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11877257 | 0.73 | PPP5C (0.48) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10978063 | 0.71 | PPP5C (0.43) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL14637039 | 0.71 | HSP90AA1 (0.61) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL5940670 | 0.71 | HSP90AA1 (0.57) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL18879467 | 0.70 | HSP90AA1 (0.60) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Pyrophosphoric Acid SCHEMBL2464363 | 0.69 | TKT (0.54) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL788235 | 0.68 | LMNA (0.67) | KDM4ETKTTDP1PPP5CHSP90AA1 | |
| Hydrochloric Acid SCHEMBL4355811 | 0.68 | TKT (0.70) | KDM4ETKTTDP1PPP5CHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100020274-A1 | COLORANT, COLOR FILTER, LCD DEVICE, COMPOSITION AND METHOD FOR PREPARING THE SAME | BOE TECHNOLOGY GROUP CO.,LTD (CN) | 2010-01-28 | — | — | US | disclosed |