Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 1.00 |
| ▸ | OSBP | P22059 | 5/20 | 1.00 |
| ▸ | OSBP2 | Q969R2 | 4/20 | 1.00 |
| ▸ | NR1H3 | Q13133 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.69 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.69 |
| ▸ | CRYAB | P02511 | 1/20 | 0.69 |
| ▸ | HMGCR | P04035 | 1/20 | 0.69 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.69 |
| ▸ | ITGAV | P06756 | 1/20 | 0.69 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670025 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL12258467 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL17858117 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL670744 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL14420779 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL289034 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL24421641 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL6388447 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL15945372 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 | |
| SCHEMBL20608159 | 1.00 | RORC (1.00) | RORCOSBPOSBP2NR1H3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029742-B2 | Compositions and methods for the repair of myelin | DUKE UNIVERSITY (US) | 2024-07-09 | — | — | US | claimed |
| WO-2024094027-A1 | BLOCKING SEQUENCE, KIT THEREOF, AND METHOD FOR USING SAME | 深圳鸿生生物科技有限公司 | 2024-05-10 | — | — | WO | claimed |
| WO-2023153464-A1 | METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION | 住友ファーマ株式会社 | 2023-08-17 | — | — | WO | claimed |
| US-20230129151-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYELIN RELATED AND INFLAMMATION RELATED DISEASES OR DISORDERS | DUKE UNIVERSITY (US) | 2023-04-27 | — | — | US | claimed |
| US-20220409632-A1 | COMPOSITIONS AND METHODS FOR THE REPAIR OF MYELIN | DUKE UNIVERSITY (US) | 2022-12-29 | — | — | US | claimed |
| EP-3911302-A1 | DRUG DELIVERY SYSTEMS CONTAINING OXIDIZED CHOLESTEROLS | Georgia Tech Research Corporation (US) | 2021-11-24 | — | — | EP | claimed |
| US-11116729-B2 | Drug delivery systems containing oxidized cholesterols | GEORGIA TECH RESEARCH CORPORATION (US) | 2021-09-14 | — | — | US | claimed |
| US-20210161916-A1 | COMPOSITIONS AND METHODS FOR THE REPAIR OF MYELIN | DUKE UNIVERSITY | 2021-06-03 | — | — | US | claimed |
| US-20200246273-A1 | DRUG DELIVERY SYSTEMS CONTAINING OXIDIZED CHOLESTEROLS | GEORGIA TECH RESEARCH CORPORATION | 2020-08-06 | — | — | US | claimed |
| WO-2020150320-A1 | DRUG DELIVERY SYSTEMS CONTAINING OXIDIZED CHOLESTEROLS | GEORGIA TECH RESEARCH CORPORATION (US) | 2020-07-23 | — | — | WO | claimed |
| EP-2771696-A2 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS AND DIFFERENTIATION OF NEONATAL ENCEPHALOPATHY | InfanDx AG (DE) | 2014-09-03 | — | — | EP | claimed |
| WO-2013060788-A2 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS AND DIFFERENTIATION OF NEONATAL ENCEPHALOPATHY | INFANDX AG (DE) | 2013-05-02 | — | — | WO | claimed |
| EP-2587264-A1 | Method and use of metabolites for the diagnosis and differentiation of neonatal encephalopathy | InfanDx AG (DE) | 2013-05-01 | — | — | EP | claimed |
| WO-2011080184-A1 | USE OF ENDOGENOUS METABOLITES FOR EARLY DIAGNOSING SEPSIS | BIOCRATES LIFE SCIENCES AG (AT) | 2011-07-07 | — | — | WO | claimed |
| EP-2339352-A1 | Use of endogenous metabolites for early diagnosing sepsis | BIOCRATES Life Sciences AG (AT) | 2011-06-29 | — | — | EP | claimed |
| US-20090202660-A1 | Agents and Methods for Osteogenic Oxysterols Inhibition of Oxidative Stress on Osteogenic Cellular Differentiation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-08-13 | — | — | US | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| WO-2005022167-A2 | COMPOUNDS THAT ACT TO MODULATE INSECT GROWTH AND METHODS AND SYSTEMS FOR IDENTIFYING SUCH COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050049230-A1 | Compounds that act to modulate insect growth and methods and systems for identifying such compounds | UNIVERSITY OF NORTH CAROLINA AT GREENSBORO, THE | 2005-03-03 | — | — | US | claimed |
| US-5856202-A | Method for determining antistreptolysin O antibody | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-01-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | RORC 660/4885OSBP 3168/4885OSBP2 3976/4885 |
| US-20230129151-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYELIN RELATED AND INFLAMMATION RELATED DISEASES OR DISORDERS | PMP22, MAG, MYT1 | RORC 9/4885OSBP 76/4885OSBP2 98/4885 |
| US-12029742-B2 | Compositions and methods for the repair of myelin | PMP22, MAG, CYP27A1 | RORC 452/4885OSBP 15/4885OSBP2 23/4885 |
| US-20050049230-A1 | Compounds that act to modulate insect growth and methods and systems for identifying such compounds | FXR2, FXR1, NR1H2 | RORC 102/4885OSBP 60/4885OSBP2 83/4885 |
| US-20210161916-A1 | COMPOSITIONS AND METHODS FOR THE REPAIR OF MYELIN | PMP22, MAG, CYP27A1 | RORC 452/4885OSBP 15/4885OSBP2 23/4885 |
| US-20220409632-A1 | COMPOSITIONS AND METHODS FOR THE REPAIR OF MYELIN | PMP22, MAG, CYP27A1 | RORC 452/4885OSBP 15/4885OSBP2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.