Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364228 | 0.91 | CRHR1 (0.46) | CRHR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3363110 | 0.82 | KDM4E (0.41) | S1PR4MEN1KMT2AHTTAGPAT2 | |
| SCHEMBL3367593 | 0.79 | CRHR1 (0.44) | CRHR1PKMALDH1A1KDM4EGAA | |
| SCHEMBL3364763 | 0.78 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3363718 | 0.78 | GABRG2 (0.42) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3366144 | 0.78 | ALDH1A1 (0.39) | S1PR4MEN1KMT2AHTTCRHR1 | |
| SCHEMBL3365035 | 0.77 | TP53 (0.39) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL3364346 | 0.77 | GABRG2 (0.43) | KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL3368213 | 0.77 | GABRG2 (0.51) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3365864 | 0.77 | CRHR1 (0.44) | MEN1KMT2AHTTCRHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |