Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697405 | 0.86 | ALDH1A1 (0.56) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL9061393 | 0.82 | MAPT (0.49) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL5666638 | 0.81 | MAPT (0.53) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL28835926 | 0.81 | MAPT (0.51) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL3361212 | 0.81 | MAPT (0.48) | RAB9ANPC1KMT2AMAPTMEN1 | |
| Methane SCHEMBL9392730 | 0.81 | MAPT (0.48) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL6593403 | 0.79 | MAPT (0.56) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL1780918 | 0.78 | ALDH1A1 (0.59) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL1446429 | 0.77 | MAPT (0.57) | RAB9AKMT2AMAPTMEN1POLB | |
| SCHEMBL3327817 | 0.76 | MAPT (0.56) | RAB9AKMT2AMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835125-B2 | Methods and compositions for selective labeling of different biotinylated targets within multicolor or multilabel assays | AFFYMETRIX, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120226027-A1 | Methods and Compositions for Selective Labeling of Different Biotinylated Targets within Multicolor or Multilabel Assays | AFFYMETRIX, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-8247540-B2 | Caged nucleotides and oligonucleotides and their application | DEITERS ALEXANDER (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100099159-A1 | CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION | DEITERS ALEXANDER | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099159-A1 | CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION | RNGTT, NT5C3B, ADAR | RAB9A 3257/4885NPC1 1018/4885KMT2A 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.