Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.66 |
| ▸ | BLM | P54132 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365605 | 1.00 | SHBG (0.68) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL7497323 | 0.88 | SHBG (0.69) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL7497316 | 0.88 | SHBG (0.69) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL9848864 | 0.88 | SHBG (0.69) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL571189 | 0.86 | SHBG (0.74) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL3946610 | 0.86 | SHBG (0.74) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL634733 | 0.86 | SHBG (0.74) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL10442230 | 0.86 | SHBG (0.67) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL10442233 | 0.86 | SHBG (0.67) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL28396227 | 0.85 | SHBG (0.65) | SHBGNR3C1ALDH1A1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | SHBG 595/4885NR3C1 527/4885ALDH1A1 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.