Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362974 | 0.83 | S1PR1 (0.47) | TRPV4ARKIF11S1PR1S1PR3 | |
| SCHEMBL3362125 | 0.81 | EGLN2 (0.50) | ARPARP10PARP11EGLN2GRM5 | |
| SCHEMBL28668535 | 0.77 | KIF11 (0.57) | TRPV4ARKIF11NSD2 | |
| SCHEMBL7604551 | 0.77 | TRPV4 (0.56) | TRPV4ARKIF11NSD2 | |
| SCHEMBL23994244 | 0.76 | AKR1C3 (0.50) | AKR1C3AKR1C2ARS1PR1S1PR3 | |
| SCHEMBL30224509 | 0.76 | AKR1C3 (0.50) | AKR1C3AKR1C2ARS1PR1S1PR3 | |
| SCHEMBL1934802 | 0.75 | GRM2 (0.43) | AKR1C3AKR1C2ARGRM5 | |
| SCHEMBL2371259 | 0.74 | AR (0.47) | TRPV4ARKIF11S1PR1S1PR3 | |
| SCHEMBL2743433 | 0.74 | MAPKAPK2 (0.48) | KIF11EGLN2GRM5 | |
| SCHEMBL249837 | 0.73 | CYP11B2 (0.54) | TRPV4ARS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |