Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365883 | 0.83 | AKR1C3 (0.50) | S1PR1S1PR3ARTRPV4NSD2 | |
| SCHEMBL3360845 | 0.78 | EGLN2 (0.48) | ARDYRK1AGSK3BCDC7CDK2 | |
| SCHEMBL3366217 | 0.78 | KCNH2 (0.52) | S1PR1DYRK1AGSK3BNOS3NOS2 | |
| SCHEMBL28668535 | 0.77 | KIF11 (0.57) | ARTRPV4NSD2KIF11 | |
| SCHEMBL7604551 | 0.77 | TRPV4 (0.56) | ARTRPV4NSD2KIF11GLA | |
| SCHEMBL3393608 | 0.76 | BACE1 (0.56) | S1PR1S1PR3PDE3BPDE3AAR | |
| SCHEMBL2371259 | 0.74 | AR (0.47) | S1PR1S1PR3ARTRPV4KIF11 | |
| SCHEMBL3397985 | 0.74 | DYRK1A (0.54) | DYRK1AGSK3BCDC7CDK2AAK1 | |
| SCHEMBL29432635 | 0.74 | DYRK1A (0.54) | DYRK1AGSK3BCDC7CDK2AAK1 | |
| SCHEMBL249837 | 0.73 | CYP11B2 (0.54) | S1PR1PDE3BPDE3AARTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |