Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366129 | 0.81 | ALOX5AP (0.45) | NUDT1GRM4TLR8ALOX5APFEN1 | |
| SCHEMBL29899251 | 0.77 | NOS3 (0.54) | NOS3NOS2NUDT1TLR8CD44 | |
| SCHEMBL2032999 | 0.71 | ASIC3 (0.57) | GRM4ASIC3ALDH1A1ALOX5APFEN1 | |
| SCHEMBL24298792 | 0.71 | NUDT1 (0.44) | NOS3NOS2NUDT1NOS1HSP90AA1 | |
| SCHEMBL29459143 | 0.71 | NUDT1 (0.44) | NOS3NOS2NUDT1NOS1HSP90AA1 | |
| SCHEMBL3398225 | 0.71 | ADORA2A (0.49) | NOS3NOS2NUDT1TLR8FGFR1 | |
| SCHEMBL16429754 | 0.69 | ALOX5AP (0.49) | NOS3NOS2ALOX5APFEN1NOS1 | |
| SCHEMBL14280828 | 0.69 | CCR1 (0.52) | NOS3NOS2TLR8CD44ALDH1A1 | |
| SCHEMBL25351761 | 0.68 | FGFR1 (0.40) | NOS3NOS2TLR8FGFR1CD44 | |
| SCHEMBL16429734 | 0.68 | FGFR1 (0.40) | NOS3NOS2TLR8FGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |