SCHEMBL3366797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL793446	0.90	MAPK1 (0.46)	MAPK1ALDH1A1TSHRTDP1ZDHHC20
	SCHEMBL664690	0.84	CA12 (0.53)	MAPK1ALDH1A1TSHRTDP1ZDHHC20
	SCHEMBL4420717	0.82	CA12 (0.54)	MAPK1ALDH1A1TSHRTDP1CA2
	SCHEMBL22343645	0.81	HDAC2 (0.49)	MAPK1ALDH1A1TSHRTDP1ZDHHC20
	SCHEMBL730168	0.79	HSD17B10 (0.54)	MAPK1ALDH1A1TSHRTDP1ZDHHC20
	SCHEMBL793119	0.79	MEN1 (0.57)	MAPK1ALDH1A1TSHRTDP1CA2
	SCHEMBL13135947	0.77	NPSR1 (0.45)	MAPK1ALDH1A1TSHRTDP1CA2
	SCHEMBL12301857	0.77	ZDHHC20 (0.52)	MAPK1ALDH1A1TSHRTDP1ZDHHC20
	SCHEMBL15963770	0.75	MAPK1 (0.51)	MAPK1ALDH1A1CA2CA12CA1
	SCHEMBL7616877	0.75	NPC1 (0.46)	ALDH1A1TSHRTDP1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.