SCHEMBL793446

SCHEMBL793446

C=CC(=O)NCCCN1CCSCC1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.46
HIF1A Q16665 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.41
GAA P10253 2/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TGM2 P21980 2/20 0.38
EPHX1 P07099 1/20 0.37
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366797 0.90 MAPK1 (0.41) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL12301857 0.88 ZDHHC20 (0.52) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL18912608 0.85 MAPK1 (0.49) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL18231989 0.83 MAPK1 (0.48) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL18359027 0.82 ZDHHC20 (0.50) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL610613 0.81 MAPK1 (0.68) MAPK1HIF1ARAB9ASMN1; SMN2GAA
SCHEMBL19955013 0.79 MAPK1 (0.44) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL15651389 0.78 GAA (0.49) MAPK1HIF1ARAB9ASMN1; SMN2TP53
SCHEMBL28722817 0.77 SIGMAR1 (0.47) MAPK1HIF1AZDHHC20ZDHHC2RAB9A
SCHEMBL10714041 0.76 MAPK1 (0.62) MAPK1HIF1AZDHHC20ZDHHC2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152362-A1 FUNCTIONAL POLYMER MEMBRANE, STACK OR DEVICE PROVIDED WITH FUNCTIONAL POLYMER MEMBRANE, AND METHOD OF PRODUCING FUNCTIONAL POLYMER MEMBRANE FUJIFILM CORPORATION (JP) 2017-06-01 US disclosed
US-20160334364-A1 GEL FOR USE IN POLYACRYLAMIDE GEL ELECTROPHORESIS AND ELECTROPHORESIS DEVICE USING SAID GEL SHARP KABUSHIKI KAISHA (JP) 2016-11-17 US disclosed
US-9359461-B2 Ethylene copolymers, compositions comprising same and preparation and treatment methods L'OREAL (FR) 2016-06-07 US disclosed
US-9359461-B2 Ethylene copolymers, compositions comprising same and preparation and treatment methods L'OREAL (FR) 2016-06-07 US disclosed
US-8753615-B2 Ethylene copolymer with PEG, cationic and anionic units, cosmetic composition including same and treatment method L'OREAL (FR) 2014-06-17 US disclosed
WO-2012175330-A2 COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT L'OREAL (FR) 2012-12-27 WO disclosed
EP-1765893-B1 NOVEL ETHYLENE COPOLYMERS, COMPOSITIONS COMPRISING SAME AND PREPARATION AND TREATMENT METHODS OREAL (FR) 2012-08-22 EP disclosed
EP-2124869-B1 POLYMER PARTICLE DISPERSION, COMPOSITION CONTAINING THE SAME AND COSMETIC TREATMENT METHOD OREAL (FR) 2012-08-15 EP disclosed
US-8178079-B2 Ethylene copolymers, compositions containing said copolymers and treatment method L'OREAL S.A. (FR) 2012-05-15 US disclosed
US-8178079-B2 Ethylene copolymers, compositions containing said copolymers and treatment method L'OREAL S.A. (FR) 2012-05-15 US disclosed
US-20080311066-A1 Cosmetics Compositions Comprising at Least One Surfactant and at Least One Novel Ethylene Copolymer with Polyethylene Glycol Grafts L'ORÉAL (FR) 2008-12-18 US disclosed
US-20080292577-A1 Novel Ethylene Copolymers, Compositions Comprising Same and Preparation and Treatment Methods L'OREAL (FR) 2008-11-27 US disclosed
US-20080292577-A1 Novel Ethylene Copolymers, Compositions Comprising Same and Preparation and Treatment Methods L'OREAL (FR) 2008-11-27 US disclosed
US-20080286218-A1 Cosmetic Compositions Containing at Least One Conditioning Agent and at Least One Ethylene Polymer with Polyethylene Glycol Grafts L'OREAL S.A. (FR) 2008-11-20 US disclosed
US-20080286218-A1 Cosmetic Compositions Containing at Least One Conditioning Agent and at Least One Ethylene Polymer with Polyethylene Glycol Grafts L'OREAL S.A. (FR) 2008-11-20 US disclosed
WO-2008104698-A2 POLYMER PARTICLE DISPERSION, COMPOSITION CONTAINING THE SAME AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2008-09-04 WO disclosed
US-20080161324-A1 Compositions and methods for treatment of viral diseases EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) 2008-07-03 US disclosed
WO-2008033466-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES COMBINATORX (SINGAPORE) PRE. LTD. (SG) 2008-03-20 WO disclosed
US-20080014154-A1 Novel Ethylene Copolymers, Compositions Containing Said Copolymers and Treatment Method L'OREAL S.A. (FR) 2008-01-17 US disclosed
US-20080014154-A1 Novel Ethylene Copolymers, Compositions Containing Said Copolymers and Treatment Method L'OREAL S.A. (FR) 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311066-A1 Cosmetics Compositions Comprising at Least One Surfactant and at Least One Novel Ethylene Copolymer with Polyethylene Glycol Grafts ACMSD, ERCC1, ASS1 MAPK1 2325/4885HIF1A 1820/4885ZDHHC20 750/4885
US-20080292577-A1 Novel Ethylene Copolymers, Compositions Comprising Same and Preparation and Treatment Methods ETV6, ASIC1, NOTUM MAPK1 2219/4885HIF1A 1203/4885ZDHHC20 2294/4885
US-20080286218-A1 Cosmetic Compositions Containing at Least One Conditioning Agent and at Least One Ethylene Polymer with Polyethylene Glycol Grafts SGMS2, SGMS1, SMS MAPK1 1815/4885HIF1A 2588/4885ZDHHC20 224/4885
US-20080161324-A1 Compositions and methods for treatment of viral diseases HAVCR2, EIF2AK2, RNASE1 MAPK1 4544/4885HIF1A 568/4885ZDHHC20 832/4885
US-20080014154-A1 Novel Ethylene Copolymers, Compositions Containing Said Copolymers and Treatment Method MMAB, SGMS2, SGMS1 MAPK1 4011/4885HIF1A 1314/4885ZDHHC20 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.