Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27502214 | 0.98 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| Hydrochloric Acid SCHEMBL9481295 | 0.95 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| SCHEMBL304712 | 0.87 | SOAT1 (0.52) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| SCHEMBL304714 | 0.87 | SOAT1 (0.52) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| SCHEMBL11146140 | 0.87 | SOAT1 (0.52) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| SCHEMBL16305051 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| Methacrylic Acid SCHEMBL28034233 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| SCHEMBL19755021 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| Ammonia Solution, Strong SCHEMBL29049234 | 0.84 | SOAT1 (0.50) | ALDH1A1LMNAHSD17B10GLO1SOAT1 | |
| Ammonia Solution, Strong SCHEMBL4866860 | 0.84 | SOAT1 (0.50) | ALDH1A1LMNAHSD17B10GLO1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | claimed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | claimed |
| EP-3118205-B1 | MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2020-04-22 | — | — | EP | disclosed |
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20140371314-A1 | Deuterated Tetramethyl Dioic Acids, Compositions Comprising Them And Uses Thereof | SYNDROMEX LTD. (IL) | 2014-12-18 | — | — | US | disclosed |
| US-8450371-B2 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA, N.V. (BE) | 2013-05-28 | — | — | US | disclosed |
| US-20120322875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2012-12-20 | — | — | US | disclosed |
| US-8258177-B2 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA, N.V. (BE) | 2012-09-04 | — | — | US | disclosed |
| US-20110294875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
| EP-1996590-A1 | SPIROINDOLINONE DERIVATIVES | F. Hoffmann-la Roche AG (CH) | 2008-12-03 | — | — | EP | disclosed |
| US-20080009486-A1 | SPIROINDOLINONE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2008-01-10 | — | — | US | disclosed |
| US-20080009486-A1 | SPIROINDOLINONE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2008-01-10 | — | — | US | disclosed |
| US-20080009486-A1 | SPIROINDOLINONE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2008-01-10 | — | — | US | disclosed |
| WO-2007104664-A1 | SPIROINDOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104664-A1 | SPIROINDOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213341-A1 | Spiroindolinone derivatives | CHEN LI | 2007-09-13 | — | — | US | disclosed |
| US-20070213341-A1 | Spiroindolinone derivatives | CHEN LI | 2007-09-13 | — | — | US | disclosed |
| US-20070213341-A1 | Spiroindolinone derivatives | CHEN LI | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | ALDH1A1 1558/4885LMNA 2440/4885HSD17B10 319/4885 |
| US-20080009486-A1 | SPIROINDOLINONE DERIVATIVES | RB1, PKD1, KRAS | ALDH1A1 156/4885LMNA 2147/4885HSD17B10 906/4885 |
| US-20110294875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | ALDH1A1 1558/4885LMNA 2440/4885HSD17B10 319/4885 |
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | KRT18, ALDH7A1, ALDH1A2 | ALDH1A1 14/4885LMNA 979/4885HSD17B10 311/4885 |
| US-20070213341-A1 | Spiroindolinone derivatives | MKI67, PKD1, RCC2 | ALDH1A1 65/4885LMNA 2188/4885HSD17B10 149/4885 |
| US-20140371314-A1 | Deuterated Tetramethyl Dioic Acids, Compositions Comprising Them And Uses Thereof | CYP27A1, GOT2, TXN2 | ALDH1A1 997/4885LMNA 2350/4885HSD17B10 211/4885 |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | KRT18, ALDH7A1, ALDH1A2 | ALDH1A1 14/4885LMNA 979/4885HSD17B10 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.