SCHEMBL3366936

SCHEMBL3366936

C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](OC(=O)c3ccccc3)CC[C@@H]12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
CYP19A1 P11511 6/20 0.57
GPBAR1 Q8TDU6 3/20 0.57
SHBG P04278 3/20 0.57
NR3C1 P04150 1/20 0.57
PGR P06401 1/20 0.57
SERPINA6 P08185 1/20 0.57
NR3C2 P08235 1/20 0.57
CYP3A4 P08684 1/20 0.57
AR P10275 1/20 0.57
HSD17B10 Q99714 1/20 0.57
MGAM O43451 1/20 0.57
AKR1B10 O60218 3/20 0.57
AKR1B1 P15121 3/20 0.57
POLB P06746 1/20 0.51
MAPK1 P28482 1/20 0.51
OR51E2 Q9H255 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4255342 1.00 MEN1 (0.67) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL6130933 0.87 MEN1 (0.58) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL14121739 0.86 ABCB1 (0.54) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL14121738 0.86 ABCB1 (0.54) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL6130951 0.86 MEN1 (0.55) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL6913689 0.85 MEN1 (0.72) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL23363784 0.84 MEN1 (0.73) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL10971884 0.84 MEN1 (0.73) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL4252612 0.84 MEN1 (0.73) MEN1KMT2ACYP19A1GPBAR1SHBG
SCHEMBL6942662 0.84 MEN1 (0.73) MEN1KMT2ACYP19A1GPBAR1SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4726059-A1 CORRELATION OF AKR1C3 ENZYME EXPRESSION LEVEL WITH KRAS MUTATION, AND MEDICAL USE Ascentawits Pharmaceuticals, Ltd. (CN) 2026-04-15 EP disclosed
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF VAN BOGAERT GINA (BE) 2026-01-15 US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 US disclosed
US-20250137012-A1 COMPOSITIONS AND METHODS OF USING TWO-PROMOTER VECTOR FOR TREATMENT OF LYSOSOMAL STORAGE DISORDERS M6P THERAPEUTICS, INC. 2025-05-01 US disclosed
CN-119630691-A Method for treating muscular dystrophy 萨勒普塔医疗公司 2025-03-14 CN disclosed
WO-2024251193-A1 CORRELATION OF AKR1C3 ENZYME EXPRESSION LEVEL WITH KRAS MUTATION, AND MEDICAL USE 深圳艾欣达伟医药科技有限公司 2024-12-12 WO disclosed
EP-4472657-A1 COMPOSITIONS AND METHODS OF USING TWO-PROMOTER VECTOR FOR TREATMENT OF LYSOSOMAL STORAGE DISORDERS M6P Therapeutics, Inc. (US) 2024-12-11 EP disclosed
CN-111741979-B Her 2-targeted antigen binding molecules comprising 4-1BBL 豪夫迈·罗氏有限公司 2024-07-02 CN disclosed
WO-2023223235-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF PURNA PHARMACEUTICALS NV (BE) 2023-11-23 WO disclosed
WO-2023150051-A1 COMPOSITIONS AND METHODS OF USING TWO-PROMOTER VECTOR FOR TREATMENT OF LYSOSOMAL STORAGE DISORDERS M6P THERAPEUTICS, INC. (US) 2023-08-10 WO disclosed
CN-109971720-B Chimeric antigen receptor modified T cells targeting ErbB receptor family and uses thereof 上海细胞治疗研究院 2023-06-20 CN disclosed
WO-2023028084-A2 METHODS AND COMPOSITIONS OF NUCLEIC ACID ENCAPSULATED WITHIN EXTERNAL MEMBRANES Coastar Therapeutics Inc. (US) 2023-03-02 WO disclosed
CN-107840888-B Mediterranean and mesomeric binding antibodies and uses thereof 希望之城公司 2022-03-29 CN disclosed
US-20100009970-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2010-01-14 US disclosed
US-20080161324-A1 Compositions and methods for treatment of viral diseases EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) 2008-07-03 US disclosed
WO-2008033466-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES COMBINATORX (SINGAPORE) PRE. LTD. (SG) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009970-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES HTR1A, HTR3B, HTR3A MEN1 3638/4885KMT2A 1108/4885CYP19A1 1933/4885
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF NR5A1, SHBG, GNRHR MEN1 748/4885KMT2A 3205/4885CYP19A1 13/4885
US-20080161324-A1 Compositions and methods for treatment of viral diseases HAVCR2, EIF2AK2, RNASE1 MEN1 4701/4885KMT2A 2353/4885CYP19A1 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.