SCHEMBL3367046

SCHEMBL3367046

O=C1CC(=O)c2cc(O)cc3oc1c(-c1ccc(O)cc1)c(=O)c23

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.50
▸ KMT2A Q03164 10/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ CYP3A4 P08684 10/20 0.49
▸ KDM4E B2RXH2 8/20 0.49
▸ MAPT P10636 8/20 0.49
▸ CYP2C9 P11712 8/20 0.49
▸ TP53 P04637 7/20 0.49
▸ ABCB1 P08183 7/20 0.49
▸ HSD17B10 Q99714 6/20 0.49
▸ ALDH1A1 P00352 6/20 0.49
▸ HPGD P15428 6/20 0.49
▸ CYP2D6 P10635 6/20 0.49
▸ ALOX15 P16050 6/20 0.49
▸ POLH Q9Y253 6/20 0.49
▸ XDH P47989 6/20 0.49
▸ CYP2C19 P33261 6/20 0.49
▸ CYP1A2 P05177 6/20 0.49
▸ DAPK1 P53355 5/20 0.49
▸ TDP1 Q9NUW8 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3470609 0.81 MEN1 (0.47) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL1133630 0.72 MEN1 (0.45) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL30684642 0.72 CYP3A4 (0.78) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL2565483 0.72 CYP3A4 (0.78) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL4104591 0.69 MEN1 (0.64) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL19934851 0.68 KDM4E (0.51) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL19929827 0.68 KDM4E (0.51) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL22142507 0.67 MEN1 (0.61) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL12940979 0.67 MEN1 (1.00) MEN1KMT2AHSP90AA1CYP3A4KDM4E
SCHEMBL5040391 0.67 MEN1 (0.70) MEN1KMT2AHSP90AA1CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161200-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE THE BOOTS COMPANY PLC (GB) 2025-05-22 — — US claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 — — US claimed
EP-4479145-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE The Boots Company PLC (GB) 2024-12-25 — — EP claimed
EP-4479146-A1 COSMETIC COMPOSITION The Boots Company PLC (GB) 2024-12-25 — — EP claimed
CN-119110720-A Cosmetic composition 布茨公司 2024-12-10 — — CN claimed
CN-116555284-B Application of GmBBX4 gene in regulating and controlling soybean isoflavone synthesis 南京农业大学 2023-12-29 — — CN claimed
WO-2023156069-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE THE BOOTS COMPANY PLC (GB) 2023-08-24 — — WO claimed
WO-2023156070-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2023-08-24 — — WO claimed
CN-116555284-A Application of GmBBX4 gene in regulating and controlling soybean isoflavone synthesis 南京农业大学 2023-08-08 — — CN claimed
EP-1359215-B1 Use of a soya cell strains with high isoflavone content NESTLE SA (CH) 2010-03-10 — — EP claimed
EP-1988891-A2 COMPOSITIONS AND METHODS FOR INDUCING BONE GROWTH AND INHIBITING BONE LOSS NESTEC S.A. (CH) 2008-11-12 — — EP claimed
EP-1956923-A1 ISOFLAVONE COMPOSITIONS FOR REDUCING ACCUMULATION OF BODY FAT IN MALE MAMMALS, AND METHODS FOR THEIR USE NESTEC S.A. (CH) 2008-08-20 — — EP claimed
WO-2007100671-A2 COMPOSITIONS AND METHODS FOR INDUCING BONE GROWTH AND INHIBITING BONE LOSS NESTEC S.A. (CH) 2007-09-07 — — WO claimed
WO-2007051629-A1 ISOFLAVONE COMPOSITIONS FOR REDUCING ACCUMULATION OF BODY FAT IN MALE MAMMALS, AND METHODS FOR THEIR USE NESTEC S.A. (CH) 2007-05-10 — — WO claimed
US-20050050589-A1 Soya cell strains with high isoflavone content NESTEC S.A. (CH) 2005-03-03 — — US claimed
EP-1501919-A1 SOYA CELL STRAINS WITH HIGH ISOFLAVONE CONTENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 2005-02-02 — — EP claimed
WO-2003093456-A1 SOYA CELL STRAINS WITH HIGH ISOFLAVONE CONTENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 2003-11-13 — — WO claimed
EP-1359215-A1 Soya cell strains with high isoflavone content SOCIETE DES PRODUITS NESTLE S.A. (CH) 2003-11-05 — — EP claimed
US-20250161200-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE THE BOOTS COMPANY PLC (GB) 2025-05-22 — — US disclosed
US-6171638-B1 Production of isoflavone enriched fractions from soy protein extracts ARCHER DANIELS MIDLAND COMPANY 2001-01-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161200-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE SGMS2, SGMS1, CERS2 MEN1 2323/4885KMT2A 3447/4885HSP90AA1 4007/4885
US-20250161201-A1 COSMETIC COMPOSITION CYP19A1, SHBG, HSD17B11 MEN1 2548/4885KMT2A 3132/4885HSP90AA1 2823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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