SCHEMBL4104591

SCHEMBL4104591

O=c1c(-c2ccc(O)cc2)c(O)oc2cc(O)cc(O)c12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.64
KMT2A Q03164 9/20 0.64
CYP3A4 P08684 8/20 0.64
KDM4E B2RXH2 7/20 0.64
MAPT P10636 6/20 0.64
TP53 P04637 6/20 0.64
CYP2C9 P11712 6/20 0.64
ALOX15 P16050 6/20 0.64
ABCB1 P08183 6/20 0.64
POLH Q9Y253 5/20 0.64
ALDH1A1 P00352 5/20 0.64
HPGD P15428 5/20 0.64
XDH P47989 5/20 0.64
DAPK1 P53355 5/20 0.64
TDP1 Q9NUW8 5/20 0.64
HDAC6 Q9UBN7 5/20 0.64
ABCG2 Q9UNQ0 5/20 0.64
CYP1A2 P05177 5/20 0.64
HIF1A Q16665 5/20 0.64
HSD17B10 Q99714 5/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22142507 0.85 MEN1 (0.61) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL5040391 0.85 MEN1 (0.70) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL14685804 0.84 GAA (0.66) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL30684642 0.84 CYP3A4 (0.78) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL2565483 0.84 CYP3A4 (0.78) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL12470191 0.84 KDM4E (0.47) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL15955977 0.83 AR (0.55) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL7087127 0.82 MEN1 (0.62) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL3358058 0.81 CYP3A4 (0.64) MEN1KMT2ACYP3A4KDM4EMAPT
SCHEMBL3051862 0.81 GLO1 (0.58) MEN1KMT2ACYP3A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112107530-B Anti-aging composition 佐登妮丝(广州)美容化妆品有限公司 2021-12-21 CN claimed
CN-112107530-A Anti-aging composition 佐登妮丝(广州)美容化妆品有限公司 2020-12-22 CN claimed
CN-114836489-B Preparation method of 3' -hydroxy genistein 佐登妮丝国际股份有限公司 2024-12-31 CN disclosed
CN-114836489-B Preparation method of 3' -hydroxy genistein 佐登妮丝国际股份有限公司 2024-12-31 CN disclosed
CN-117837498-A Method for improving and regulating synthesis of flavonoids in saussurea involucrata leaves 石河子大学 2024-04-09 CN disclosed
CN-116509839-A Application of 6-hydroxy genistein in preparing anti-altitude anoxia medicine 西安交通大学医学院第一附属医院 2023-08-01 CN disclosed
CN-116407532-A Application of 8-hydroxy genistein in preparing medicine for resisting altitude anoxia 马慧萍 2023-07-11 CN disclosed
US-20230190702-A1 A COMPOSITION FOR IMPROVING QOL OF A 40-YEAR-OLD OR OLDER POSTMENOPAUSAL WOMAN WITHOUT MENOPAUSAL DISORDER DAICEL CORPORATION (JP) 2023-06-22 US disclosed
CN-115697086-A Composition for improving QOL of women over 40 years old without climacteric disturbance after amenorrhea 株式会社大赛璐 2023-02-03 CN disclosed
CN-114836489-A Preparation method of 3' -hydroxy genistein 佐登妮丝国际股份有限公司 2022-08-02 CN disclosed
CN-114836489-A Preparation method of 3' -hydroxy genistein 佐登妮丝国际股份有限公司 2022-08-02 CN disclosed
CN-107441079-B Medicine for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof 四川省中医药科学院 2021-03-26 CN disclosed
WO-2017065515-A1 COMPOSITION FOR PREVENTING OR TREATING GYNECOLOGICAL CANCERS AND MENOPAUSAL SYMPTOMS CONTAINING FLEMINGIA STROBILIFERA EXTRACT OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2017-04-20 WO disclosed
EP-2672964-B1 COMPOSITION FOR USE IN THE TREATMENT OF MENOPAUSE PROBLEMS/DISORDERS PALADIN PHARMA S P A (IT) 2016-06-01 EP disclosed
EP-2672964-A1 COMPOSITION FOR USE IN THE TREATMENT OF MENOPAUSE PROBLEMS/DISORDERS AND IN THE TREATMENT OF GENERAL AGING OF THE ORGANISM Paladin Pharma S.p.A. (IT) 2013-12-18 EP disclosed
WO-2012107905-A1 COMPOSITION FOR USE IN THE TREATMENT OF MENOPAUSE PROBLEMS/DISORDERS AND IN THE TREATMENT OF GENERAL AGING OF THE ORGANISM. PALADIN PHARMA S.P.A. (IT) 2012-08-16 WO disclosed
US-20090221690-A1 Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (US) 2009-09-03 US disclosed
US-7084265-B1 Polynucleotide encoding 2-hydroxyisoflavanone synthase NIHON UNIVERSITY (JP) 2006-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221690-A1 Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof SOST, BPGM, PTMS MEN1 197/4885KMT2A 4140/4885CYP3A4 702/4885
US-20230190702-A1 A COMPOSITION FOR IMPROVING QOL OF A 40-YEAR-OLD OR OLDER POSTMENOPAUSAL WOMAN WITHOUT MENOPAUSAL DISORDER SHBG, UBQLN2, ELOVL5 MEN1 3066/4885KMT2A 3713/4885CYP3A4 4418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.