SCHEMBL3470609

SCHEMBL3470609

O=C1CC(=O)c2oc3cc(O)cc(c3c(=O)c2-c2ccc(O)cc2)O1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.47
▸ KMT2A Q03164 9/20 0.47
▸ HSP90AA1 P07900 1/20 0.47
▸ KDM4E B2RXH2 10/20 0.46
▸ CYP3A4 P08684 9/20 0.46
▸ MAPT P10636 8/20 0.46
▸ CYP2C9 P11712 7/20 0.46
▸ HSD17B10 Q99714 7/20 0.46
▸ TP53 P04637 6/20 0.46
▸ ALDH1A1 P00352 6/20 0.46
▸ ALOX15 P16050 6/20 0.46
▸ CYP2D6 P10635 5/20 0.46
▸ POLH Q9Y253 5/20 0.46
▸ HPGD P15428 5/20 0.46
▸ ABCB1 P08183 5/20 0.46
▸ CYP2C19 P33261 4/20 0.46
▸ APP P05067 4/20 0.46
▸ CSNK2A2 P19784 4/20 0.46
▸ XDH P47989 4/20 0.46
▸ DAPK1 P53355 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31260540 0.84 MEN1 (0.41) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL3367046 0.81 MEN1 (0.50) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL2565483 0.69 CYP3A4 (0.78) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL30684642 0.69 CYP3A4 (0.78) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL4104591 0.66 MEN1 (0.64) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL5040391 0.64 MEN1 (0.70) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL12940979 0.64 MEN1 (1.00) MEN1KMT2AHSP90AA1KDM4ECYP3A4
SCHEMBL22142507 0.64 MEN1 (0.61) MEN1KMT2AHSP90AA1KDM4ECYP3A4
Kaempferol SCHEMBL1259228 0.64 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4MAPT
Kaempferol SCHEMBL30655455 0.64 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1956923-A1 ISOFLAVONE COMPOSITIONS FOR REDUCING ACCUMULATION OF BODY FAT IN MALE MAMMALS, AND METHODS FOR THEIR USE NESTEC S.A. (CH) 2008-08-20 — — EP claimed
WO-2007051629-A1 ISOFLAVONE COMPOSITIONS FOR REDUCING ACCUMULATION OF BODY FAT IN MALE MAMMALS, AND METHODS FOR THEIR USE NESTEC S.A. (CH) 2007-05-10 — — WO claimed
CN-110087661-B Aglycone production promoter 森永乳业株式会社 2022-10-21 — — CN disclosed
US-11160755-B2 Amphiphilic polymer LG CHEM, LTD. (KR) 2021-11-02 — — US disclosed
CN-109312035-B Amphiphilic polymers 株式会社LG化学 2021-07-30 — — CN disclosed
US-20210205344-A1 COMPOSITION CONTAINING FLAVONOID-CYCLODEXTRIN CLATHRATE COMPOUND TAIYO KAGAKU CO., LTD. (JP) 2021-07-08 — — US disclosed
US-11034786-B2 Amphiphilic triblock polymer LG CHEM, LTD. (KR) 2021-06-15 — — US disclosed
CN-109153758-B Amphiphilic triblock polymers 株式会社LG化学 2021-04-27 — — CN disclosed
EP-3805399-A1 COMPOSITION CONTAINING FLAVONOID-CYCLODEXTRIN CLATHRATE COMPOUND Taiyo Kagaku Co., Ltd. (JP) 2021-04-14 — — EP disclosed
CN-107207736-B Amphiphilic polymers 株式会社LG化学 2021-04-02 — — CN disclosed
CN-112538439-A Lactobacillus plantarum and application thereof in preparing plant coagulated yoghurt and improving intestinal bacterial facies 欧斐生 2021-03-23 — — CN disclosed
EP-3205688-A1 AMPHIPHILIC POLYMER LG Chem, Ltd. (KR) 2017-08-16 — — EP disclosed
US-20170143628-A1 AMPHIPHILIC POLYMER LG CHEM, LTD. (KR) 2017-05-25 — — US disclosed
EP-2208422-B1 Compositions and methods for reducing or preventing obesity NESTEC SA (CH) 2015-11-25 — — EP disclosed
EP-1750523-B1 COMPOSITIONS AND METHODS FOR REDUCING OR PREVENTING OBESITY NESTEC SA (CH) 2010-07-21 — — EP disclosed
EP-2208422-A1 Compositions and methods for reducing or preventing obesity Nestec S.A. (CH) 2010-07-21 — — EP disclosed
EP-1988891-A2 COMPOSITIONS AND METHODS FOR INDUCING BONE GROWTH AND INHIBITING BONE LOSS NESTEC S.A. (CH) 2008-11-12 — — EP disclosed
WO-2007100671-A2 COMPOSITIONS AND METHODS FOR INDUCING BONE GROWTH AND INHIBITING BONE LOSS NESTEC S.A. (CH) 2007-09-07 — — WO disclosed
EP-1750523-A1 COMPOSITIONS AND METHODS FOR REDUCING OR PREVENTING OBESITY Nestec S.A. (CH) 2007-02-14 — — EP disclosed
WO-2005089567-A1 COMPOSITIONS AND METHODS FOR REDUCING OR PREVENTING OBESITY NESTEC S.A. (CH) 2005-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11034786-B2 Amphiphilic triblock polymer ABCB4, LIPA, CETP MEN1 3864/4885KMT2A 4752/4885HSP90AA1 2210/4885
US-11160755-B2 Amphiphilic polymer LIPA, CETP, ABCB4 MEN1 2999/4885KMT2A 4385/4885HSP90AA1 2134/4885
US-20170143628-A1 AMPHIPHILIC POLYMER ABCB11, LIPA, SLC10A2 MEN1 2007/4885KMT2A 4815/4885HSP90AA1 3679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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