Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18124081 | 0.98 | CA4 (0.41) | CA4CPT2ACLY | |
| Potassium Ion SCHEMBL1767658 | 0.98 | CA4 (0.41) | CA4CPT2ACLY | |
| Potassium Ion SCHEMBL29489145 | 0.98 | CA4 (0.41) | CA4CPT2ACLY | |
| SCHEMBL1767657 | 0.98 | CA4 (0.41) | CA4CPT2ACLY | |
| SCHEMBL31473016 | 0.96 | CA4 (0.48) | CA4CPT2ACLY | |
| SCHEMBL1460547 | 0.96 | CA4 (0.43) | CA4CPT2ACLY | |
| Zinc Ion SCHEMBL2315207 | 0.96 | CA4 (0.43) | CA4CPT2ACLY | |
| SCHEMBL965645 | 0.96 | CA4 (0.48) | CA4CPT2ACLY | |
| SCHEMBL990294 | 0.96 | CA4 (0.43) | CA4CPT2ACLY | |
| Potassium Ion SCHEMBL337213 | 0.96 | CA4 (0.43) | CA4CPT2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118956849-A | Preparation method of immobilized lipase and application of immobilized lipase in catalytic synthesis of glyceride | 广东药科大学 | 2024-11-15 | — | — | CN | claimed |
| CN-116549427-A | New use of hydroxycitric acid for treating cholelithiasis and cholecystitis induced by cholelithiasis | 时珍本草生物科技(中山)有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-110363765-B | Osteoporosis parameter automatic measurement method based on CT image | 江苏天影医疗科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-108047029-A | A kind of preparation method of the extraction purification hydroxycitric acid from Garcinia Cambogia | 南京慧博生物科技有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-104844447-B | Method for preparing high-purity hydroxycitric acid with garcinia cambogia as raw material | 义乌章舸生物工程有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-104844447-A | Method for preparing high-purity hydroxycitric acid with garcinia cambogia as raw material | JIANGR BIO TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-104725218-A | Method for extracting and purifying hydroxycitric acid from garcinia cambogia | LI YUSHAN | 2015-06-24 | — | — | CN | claimed |
| US-7858128-B2 | Hydroxycitric acid compositions, pharmaceutical and dietary supplements and food products made therefrom, and methods for their use in reducing body weight | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2010-12-28 | — | — | US | claimed |
| US-20090155391-A1 | HYDROXYCITRIC ACID SALT COMPOSITION AND METHOD OF USE FOR REDUCING BODY WEIGHT | UNIBAR CORPORATION (US) | 2009-06-18 | — | — | US | claimed |
| US-7507421-B2 | Hydroxycitric acid salt composition and method of making | UNIBAR CORPORATION (US) | 2009-03-24 | — | — | US | claimed |
| WO-2005085164-A1 | NOVEL TRIPLE MINERAL SALTS OF (-)-HYDROXYCITRIC ACID AND PROCESSES FOR PREPARING THE SAME | GOKARAJU GANGA RAJU (IN) | 2005-09-15 | — | — | WO | claimed |
| US-20040259937-A1 | Hydroxycitric acid complex metal salts, composition, and methods | INDFRAG LIMITED (IN) | 2004-12-23 | — | — | US | claimed |
| US-20040219124-A1 | Cosmetic and Pharmaceutical Masks Based on Ion-Pair Delivery System | GUPTA SHYAM K (US) | 2004-11-04 | — | — | US | claimed |
| WO-2003092730-A1 | HYDROXYCITRIC ACID SALT COMPOSITION AND METHOD OF MAKING | UNIBAR CORPORATION (US) | 2003-11-13 | — | — | WO | claimed |
| US-20030207942-A1 | Hydroxycitric acid salt composition and method of making | UNIBAR CORPORATION (US) | 2003-11-06 | — | — | US | claimed |
| EP-0787489-B1 | Composition containing propionyl-L-carnitine and hydroxycitric acid or pantothenic acid | SIGMA TAU HEALTHSCIENCE SPA (IT) | 2003-07-30 | — | — | EP | claimed |
| US-20010011081-A1 | Pharmaceutical composition comprising L- carnitine or alkanoyl L-carnitine for the prevention and treatment of diseases brought about by lipid metabolism disorders | SIGMA-TAU INDUSTRIE PARMACEUTICHE RIUNITE S.P.A. (IT) | 2001-08-02 | — | — | US | claimed |
| US-6217898-B1 | ANTICHOLESTEROL AGENTS | SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) | 2001-04-17 | — | — | US | claimed |
| WO-2000015051-A1 | HYDROXYCITRIC ACID COMPOSITIONS | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2000-03-23 | — | — | WO | claimed |
| EP-0787489-A2 | Composition containing L-carnitine or alkanoyl-L-carnitine and hydroxycitric acid or pantothenic acid | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1997-08-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155391-A1 | HYDROXYCITRIC ACID SALT COMPOSITION AND METHOD OF USE FOR REDUCING BODY WEIGHT | HCAR1, HCAR2, HCAR3 | CA4 134/4885CPT2 194/4885ACLY 376/4885 |
| US-20030207942-A1 | Hydroxycitric acid salt composition and method of making | HCAR1, HCAR2, HAAO | CA4 153/4885CPT2 845/4885ACLY 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.