SCHEMBL3369176

SCHEMBL3369176

C#CCNS(=O)(=O)c1ccc(OC)cc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.65
PKM P14618 1/20 0.65
SMN1; SMN2 Q16637 2/20 0.59
CYP19A1 P11511 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
MMP1 P03956 1/20 0.56
MMP2 P08253 1/20 0.56
MMP9 P14780 1/20 0.56
MMP8 P22894 1/20 0.56
MMP13 P45452 1/20 0.56
POLB P06746 2/20 0.55
MEP1B Q16820 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
USP2 O75604 1/20 0.52
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3091205 0.95 ALDH1A1 (0.59) ALDH1A1PKMSMN1; SMN2CYP19A1CA1
SCHEMBL20390809 0.85 ALDH1A1 (0.69) ALDH1A1PKMSMN1; SMN2CYP19A1CA1
SCHEMBL28109027 0.83 ALDH1A1 (0.61) ALDH1A1PKMSMN1; SMN2CA1CA2
SCHEMBL25379509 0.83 ALDH1A1 (0.49) ALDH1A1PKMSMN1; SMN2MMP1MMP2
SCHEMBL28400660 0.82 MMP2 (0.57) ALDH1A1SMN1; SMN2CA1CA2MMP1
SCHEMBL25431630 0.82 FFAR4 (0.51) ALDH1A1PKMSMN1; SMN2CYP19A1CA1
SCHEMBL5563528 0.82 ALDH1A1 (0.86) ALDH1A1PKMSMN1; SMN2CYP19A1CA1
SCHEMBL1619896 0.80 ALDH1A1 (0.71) ALDH1A1PKMSMN1; SMN2CYP19A1CA1
SCHEMBL2624207 0.80 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2CYP19A1CA1CA2
SCHEMBL3094703 0.80 ALDH1A1 (0.56) ALDH1A1PKMSMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008288-A Benzsulfamide compound and application thereof 西北农林科技大学 2016-10-12 CN claimed
EP-0929519-B1 BETA-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS UPJOHN CO (US) 2005-02-23 EP claimed
US-20250170104-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2025-05-29 US disclosed
EP-4486452-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASSS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-01-08 EP disclosed
WO-2023166039-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-07 WO disclosed
WO-2023166039-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-07 WO disclosed
CN-107344940-B BTK inhibitors and uses thereof 广东东阳光药业有限公司 2020-04-21 CN disclosed
EP-1628957-B1 SULFOPYRROLES TAKEDA PHARMACEUTICAL (JP) 2010-09-29 EP disclosed
US-7612064-B2 Sulfopyrroles TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-03 US disclosed
US-20070060570-A1 Sulfopyrroles TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-15 US disclosed
EP-1655284-A1 2-Phenylsulfopyrroles Aponetics AG (CH) 2006-05-10 EP disclosed
EP-1628957-A1 SULFOPYRROLES Takeda Pharmaceutical Company Limited (JP) 2006-03-01 EP disclosed
WO-2004103968-A1 SULFOPYRROLES APONETICS AG (CH) 2004-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060570-A1 Sulfopyrroles TYK2, ARSA, SULT2A1 ALDH1A1 1078/4885PKM 1217/4885SMN1; SMN2 2378/4885
US-20250170104-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß LTA, SERPINB1, LAS1L ALDH1A1 3061/4885PKM 3730/4885SMN1; SMN2 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.