Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15096157 | 0.81 | MAPT (0.51) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7089861 | 0.79 | MAPT (0.50) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7089859 | 0.79 | MAPT (0.50) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| SCHEMBL24434915 | 0.79 | MAPK9 (0.50) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| SCHEMBL109232 | 0.78 | CYP3A4 (0.53) | MAPK9TSHRNPSR1MAPTCYP3A4 | |
| SCHEMBL15091391 | 0.78 | MAPT (0.60) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| SCHEMBL24564668 | 0.78 | MAPT (0.60) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| SCHEMBL1260710 | 0.77 | MAPK9 (0.77) | MAPK9TSHRNPSR1MAPTCYP3A4 | |
| SCHEMBL17761560 | 0.76 | MAPT (0.59) | MAPK9TSHRNPSR1MAPTL3MBTL1 | |
| SCHEMBL15091787 | 0.76 | L3MBTL1 (0.65) | MAPK9TSHRNPSR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343118-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | DUKE UNIVERSITY | 2014-11-20 | — | — | US | disclosed |
| US-20130178520-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | DUKE UNIVERSITY (US) | 2013-07-11 | — | — | US | disclosed |
| EP-1401388-B1 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2010-06-16 | — | — | EP | disclosed |
| US-7704942-B2 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2010-04-27 | — | — | US | disclosed |
| US-20050042255-A1 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2005-02-24 | — | — | US | disclosed |
| EP-1401388-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | Givaudan SA (CH) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003002084-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2003-01-09 | — | — | WO | disclosed |
| EP-1269982-A1 | Fragrance and flavour compositions | Givaudan SA (CH) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343118-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | BRCA1, NAT1, AADAC | MAPK9 3875/4885TSHR 423/4885NPSR1 3482/4885 |
| US-20050042255-A1 | Fragrance and flavour compositions | C5, FAAH2, TRPA1 | MAPK9 3225/4885TSHR 3237/4885NPSR1 376/4885 |
| US-20130178520-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | SNCA, PARK7, PNMT | MAPK9 4307/4885TSHR 1034/4885NPSR1 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.