SCHEMBL3371358

SCHEMBL3371358

COC1c2ccccc2Oc2ccc3ccccc3c21

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
TAAR1 Q96RJ0 1/20 0.40
KCNA3 P22001 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
AVPR1B P47901 1/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127602 0.78 MAOA (0.52) CYP1A2CYP2C19KCNA3NPSR1MAOA
SCHEMBL12845408 0.77 CYP1A2 (0.46) CYP1A2CYP2C19KCNA3NPSR1
SCHEMBL18287902 0.76 MAOA (0.58) CYP1A2CYP2C19TAAR1NPSR1MAOA
SCHEMBL28403792 0.76 CYP1A2 (0.47) CYP1A2CYP2C19TAAR1NPSR1AVPR1B
SCHEMBL29563431 0.75 HPGD (0.51) CYP1A2CYP2C19NPSR1
SCHEMBL22167524 0.75 CYP1A2 (0.49) CYP1A2CYP2C19TAAR1NPSR1MAOA
SCHEMBL416287 0.73 CYP1A2 (0.62) CYP1A2CYP2C19TAAR1NPSR1
SCHEMBL416279 0.72 CYP1A2 (0.53) CYP1A2CYP2C19TAAR1NPSR1AVPR1B
SCHEMBL8817146 0.72 ATM (0.49) CYP1A2CYP2C19NPSR1
SCHEMBL22167523 0.71 CYP1A2 (0.44) CYP1A2CYP2C19NPSR1AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781247-B1 COSMETIC COMPOSITIONS CONTAINING FLUORESCENT COLORANTS FOR NATURAL SKIN APPEARANCE BASF SE (DE) 2010-11-03 EP disclosed
EP-1781247-A1 COSMETIC COMPOSITIONS CONTAINING FLUORESCENT COLORANTS FOR NATURAL SKIN APPEARANCE Ciba Specialty Chemicals Holding Inc. (CH) 2007-05-09 EP disclosed
US-20060078518-A1 Cosmetic compositions containing fluorescent colorants for natural skin appearance ELDER STEWART T 2006-04-13 US disclosed
WO-2006021527-A1 COSMETIC COMPOSITIONS CONTAINING FLUORESCENT COLORANTS FOR NATURAL SKIN APPEARANCE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060078518-A1 Cosmetic compositions containing fluorescent colorants for natural skin appearance CUTA, MITF, RARA CYP1A2 3744/4885CYP2C19 3609/4885TAAR1 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.