Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457804 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDCYP2C9 | |
| SCHEMBL8799913 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL1422872 | 0.73 | CYP11B2 (0.48) | CNR2CYP2D6 | |
| SCHEMBL66294 | 0.72 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4ETNFNOD2NOD1 | |
| SCHEMBL2885907 | 0.71 | HTT (0.55) | SMN1; SMN2ALDH1A1KDM4ETNFLMNA | |
| SCHEMBL31267409 | 0.70 | TP53 (0.55) | — | |
| SCHEMBL1416101 | 0.67 | NOD1 (0.41) | SMN1; SMN2ALDH1A1KDM4EHPGDNOD1 | |
| SCHEMBL30218661 | 0.67 | POLB (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDTNF | |
| SCHEMBL1422459 | 0.67 | HPGD (0.50) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23855754 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHPGDNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | disclosed |