Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341802 | 0.76 | TSHR (0.49) | MAPTMITFSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11821757 | 0.74 | SKP2 (0.43) | CA2SMN1; SMN2SKP2POLBALDH1A1 | |
| SCHEMBL83731 | 0.72 | ALDH1A1 (0.50) | MAPTKCNH2STING1PLK1CA2 | |
| SCHEMBL12708634 | 0.71 | ALDH1A1 (0.50) | MAPTKCNH2CA2SMN1; SMN2SKP2 | |
| SCHEMBL11490171 | 0.70 | MAPT (0.54) | MAPTKCNH2STING1CA2SMN1; SMN2 | |
| SCHEMBL9513445 | 0.70 | VCAM1 (0.55) | VCAM1POLBALDH1A1KDM4E | |
| SCHEMBL28185595 | 0.70 | TSHR (0.51) | MAPTKCNH2STING1CA2SMN1; SMN2 | |
| SCHEMBL1025706 | 0.70 | POLB (0.51) | MAPTCA2SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2647110 | 0.70 | SKP2 (0.56) | MAPTKCNH2CA2SMN1; SMN2SKP2 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL105454 | 0.69 | MAPT (0.56) | MAPTMITFPOLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |