Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557822 | 0.67 | BRPF1 (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL3515106 | 0.67 | ADORA2B (0.38) | KDM4EALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL3230718 | 0.67 | BRPF1 (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| Hydrochloric Acid SCHEMBL3987570 | 0.66 | BRPF1 (0.48) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30448847 | 0.64 | MAPT (0.37) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL3106709 | 0.64 | SLC22A12 (0.36) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL3093956 | 0.64 | MAPT (0.37) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL29049748 | 0.64 | — | — | |
| SCHEMBL3098956 | 0.62 | TGFBR1 (0.32) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL3513011 | 0.61 | PDE4A (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |