Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898502 | 0.82 | KIF11 (0.50) | ARNOTUMMOGAT2KIF11 | |
| SCHEMBL3433509 | 0.81 | OTUD7B (0.48) | PGRXDH | |
| SCHEMBL3434306 | 0.76 | ABL1 (0.44) | NOTUMKIF11 | |
| SCHEMBL8015401 | 0.75 | IKBKB (0.41) | ARNOTUMPARP10PARP11PGR | |
| SCHEMBL14499205 | 0.71 | PGR (0.42) | ARPGR | |
| SCHEMBL3020986 | 0.70 | PGR (0.55) | PGR | |
| SCHEMBL3020600 | 0.70 | PGR (0.65) | NOTUMPARP10PARP11PGRKIF11 | |
| SCHEMBL4170374 | 0.70 | PGR (0.71) | ARPGRMAPT | |
| SCHEMBL29678302 | 0.70 | TSHR (0.58) | NOTUMPGRKIF11ASIC3MAOB | |
| SCHEMBL1263144 | 0.70 | TSHR (0.58) | NOTUMPGRKIF11ASIC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |