Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 9/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434306 | 0.88 | ABL1 (0.44) | ABL1SCN9AADAMTS5CES1 | |
| SCHEMBL3377336 | 0.81 | AR (0.45) | PGRXDH | |
| SCHEMBL14499205 | 0.71 | PGR (0.42) | PGR | |
| SCHEMBL3468129 | 0.71 | KIF11 (0.69) | OTUD7BPGRABL1 | |
| SCHEMBL3016588 | 0.71 | PGR (0.51) | OTUD7BPGRADAMTS5 | |
| SCHEMBL3466905 | 0.69 | OTUD7B (0.52) | OTUD7BABL1SCN9AXDHCES1 | |
| SCHEMBL1044062 | 0.69 | CYP1A2 (0.51) | XDH | |
| SCHEMBL5840598 | 0.68 | SLC13A5 (0.51) | XDH | |
| SCHEMBL2380991 | 0.68 | XDH (0.49) | XDH | |
| SCHEMBL30996181 | 0.68 | ABL1 (0.61) | PGRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |