Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335811 | 0.75 | S100A4 (0.40) | PTPRCKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29725127 | 0.75 | S100A4 (0.40) | PTPRCKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30493712 | 0.73 | ABCG2 (0.38) | ABCG2 | |
| SCHEMBL1864060 | 0.73 | ABCG2 (0.38) | ABCG2 | |
| SCHEMBL8342519 | 0.72 | PTPRC (0.41) | PTPRCKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8987959 | 0.72 | ABCG2 (0.33) | ABCG2 | |
| Hydrochloric Acid SCHEMBL7340960 | 0.72 | ABCG2 (0.37) | ABCG2 | |
| SCHEMBL29555333 | 0.71 | ABCG2 (0.37) | ABCG2CDC25BCDC25A | |
| SCHEMBL49498 | 0.67 | PTPRC (0.39) | PTPRCIDO1PTPN1KDM4EMEN1 | |
| SCHEMBL527160 | 0.67 | ABCG2 (0.46) | ABCG2PTPRCIDO1PTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9012555-A | — | — | None | — | — | JP | disclosed |
| JP-9025267-A | — | — | None | — | — | JP | disclosed |
| CN-113651755-B | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113651755-A | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-106831581-B | Azaspiro-bifluorene derivative and preparation method thereof | 上海大学 | 2021-07-09 | — | — | CN | disclosed |
| EP-1844060-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-11-17 | — | — | EP | disclosed |
| US-20080161567-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | US | disclosed |
| EP-1844060-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081973-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2006-08-10 | — | — | WO | disclosed |
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |
| US-5300642-A | α, α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532054-A1 | Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0137333-B1 | SPIRO-TRICYCLICAROMATIC SUCCINIMIDE DERIVATIVES AS INHIBITORS OF ALDOSE REDUCTASE | ALCON LABORATORIES, INC. (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | disclosed |
| US-5153211-A | Enzyme inhibitors | ALCON LABORATORIES, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4864028-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0137333-A2 | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase | ALCON LABORATORIES, INC. (US) | 1985-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161567-A1 | Metal Complexes | SOD1, AP1M1, AP2A1 | ABCG2 3444/4885PTPRC 2218/4885IDO1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.