2-Pyrrolidone

2-Pyrrolidone

SCHEMBL3378461

C=COC(=O)C=C.O=C1CCCN1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.52
CRBN Q96SW2 2/20 0.45
FKBP5 Q13451 1/20 0.45
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL4595907 0.83 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL22534 0.83 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
Acrylic Acid Methyl Ester SCHEMBL4203174 0.83 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL933908 0.81 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28565455 0.81 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL2110293 0.80 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28279632 0.80 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4193115 0.80 OR51E2 (0.62) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL11253981 0.80 OR51E2 (0.62) OR51E2CRBNFKBP5KDM4EGAA
Acrylic Acid Ethyl Ester SCHEMBL2492791 0.79 OR51E2 (0.47) OR51E2CRBNFKBP5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490536-A Biodegradable delivery particles 恩盖普有限公司 2023-07-25 CN claimed
CN-110392731-A Benefit agent containing delivery particles 宝洁公司 2019-10-29 CN claimed
CN-101039723-B Personal care compositions comprising visible beads, cationic polymer, and surfactant PROCTER & GAMBLE 2013-06-19 CN claimed
CN-1203840-C Cleaning composition PROCTER & GAMBLE (US) 2005-06-01 CN claimed
US-6699824-B1 RINSE-OFF LIQUID PERSONAL CLEANSING COMPOSITION COMPRISING WATER, WATER SOLUBLE SURFACTANT, WATER INSOLUBLE OIL SELECTED FROM HIGHLY BRANCHED POLYALPHAOLEFINS, SELECTED HYDROPHOBIC SKIN ACTIVE COMPONENT THE PROCTER & GAMBLE COMPANY 2004-03-02 US claimed
US-20020128162-A1 CLEANSING COMPOSITIONS PROCTER & GAMBLE COMPANY, THE 2002-09-12 US claimed
US-6444629-B1 RINSE-OFF PERSONAL CLEANSING COMPOSITION COMPRISING CRYSTALLIZING ANIONIC SURFACTANT, SECOND, DIFFERENT SURFACTANT, WATER INSOLUBLE OIL, PETROLATUM AND MINERAL OIL, AND WATER THE PROCTER & GAMBLE COMPANY 2002-09-03 US claimed
EP-1011625-B1 CLEANSING COMPOSITIONS PROCTER & GAMBLE (US) 2002-08-14 EP claimed
CN-1341012-A Cleaning composition PROCTER & GAMBLE (US) 2002-03-20 CN claimed
CN-1080557-C Cleansing compositions PROCTER & GAMBLE (US) 2002-03-13 CN claimed
WO-1999009947-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009950-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009951-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009948-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009946-A1 CLEANSING COMPOSITIONS BASED ON HYDROPHOBICALLY MODIFIED SILICONES THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009949-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
EP-0197649-B1 LIQUID CLEANSING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1990-05-30 EP claimed
US-4678606-A Liquid cleansing composition THE PROCTER & GAMBLE COMPANY (US) 1987-07-07 US claimed
EP-0197649-A2 Liquid cleansing composition THE PROCTER & GAMBLE COMPANY (US) 1986-10-15 EP claimed
US-4438095-A New cosmetic compositions for hair or skin conditioning, and the application thereof SOCIETE ANONYME DITE: L'OREAL (FR) 1984-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128162-A1 CLEANSING COMPOSITIONS DEGS1, CUTA, CCR1 OR51E2 550/4885CRBN 2075/4885FKBP5 4404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.