2-Pyrrolidone

2-Pyrrolidone

SCHEMBL28565455

C=C.C=COC(C)=O.O=C1CCCN1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.50
CRBN Q96SW2 2/20 0.44
FKBP5 Q13451 1/20 0.44
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL22534 0.98 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4595907 0.98 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL933908 0.97 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27876042 0.94 OR51E2 (0.47) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL852356 0.90 OR51E2 (0.43) OR51E2CRBNFKBP5
Caprolactam SCHEMBL28156132 0.86 FKBP5 (0.46) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27365042 0.84 OR51E2 (0.47) OR51E2CRBNFKBP5KDM4EGAA
Itaconate SCHEMBL4960729 0.84 ALOX15 (0.40) OR51E2CRBNFKBP5
2-Pyrrolidone SCHEMBL28279632 0.82 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL3378461 0.81 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112741897-A Composition of micro-array drug delivery system of glucagon-like peptide-1 receptor agonist 南京滕恩医药有限公司 2021-05-04 CN disclosed
CN-112741798-A Preparation process of micro-array drug delivery system of glucagon-like peptide-1 receptor agonist 南京滕恩医药有限公司 2021-05-04 CN disclosed