2-Pyrrolidone

2-Pyrrolidone

SCHEMBL22534

C=COC(C)=O.O=C1CCCN1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.52
CRBN Q96SW2 2/20 0.45
FKBP5 Q13451 1/20 0.45
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL4595907 1.00 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL933908 0.98 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28565455 0.98 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27876042 0.95 OR51E2 (0.47) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL852356 0.91 OR51E2 (0.43) OR51E2CRBNFKBP5ALDH1A1
Caprolactam SCHEMBL28156132 0.88 FKBP5 (0.46) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27365042 0.85 OR51E2 (0.47) OR51E2CRBNFKBP5KDM4EGAA
Itaconate SCHEMBL4960729 0.85 ALOX15 (0.40) OR51E2CRBNFKBP5
2-Pyrrolidone SCHEMBL28279632 0.83 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL3378461 0.83 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199933-A1 A FIBRE BINDER COMPOSITION FOR RETAINING FIBRES AND OTHER PARTICLES ON A BUILDING SITE ADMANSTARS B.V (NL) 2024-06-20 US claimed
EP-4323453-A1 A FIBRE BINDER COMPOSITION FOR RETAINING FIBRES AND OTHER PARTICLES ON A BUILDING SITE Fiberbinder ApS (DK) 2024-02-21 EP claimed
US-20230398108-A1 Pharmaceutical Compositions of a Kinase Inhibitor EXELIXIS, INC. 2023-12-14 US claimed
EP-4240333-A1 PHARMACEUTICAL COMPOSITIONS OF A KINASE INHIBITOR Exelixis, Inc. (US) 2023-09-13 EP claimed
CN-116710092-A Composition for oral administration of efroconazole 大峰LS株式会社 2023-09-05 CN claimed
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients THE PROCTER & GAMBLE COMPANY (US) 2023-06-06 US claimed
CN-115710559-A Methods and compositions for improving corn yield 新叶共生有限公司 2023-02-24 CN claimed
EP-4017563-A1 NITRIC OXIDE GENERATING SYSTEMS Nota Laboratories, LLC (US) 2022-06-29 EP claimed
US-20220176062-A1 NITRIC OXIDE GENERATING SYSTEMS NOTA Laboratories, LLC 2022-06-09 US claimed
CN-110636837-B Pharmaceutical composition of CYP17 inhibitor and preparation method thereof 江苏恒瑞医药股份有限公司 2022-05-24 CN claimed
WO-2005123024-A1 TOOTH WHITENING PRODUCTS AND METHODS OF MAKING THE SAME LORNAMEAD BRANDS, INC. (US) 2005-12-29 WO claimed
US-20050276760-A1 Tooth for whitening products and methods of making the same LORNAMEAD BRANDS, INC. (US) 2005-12-15 US claimed
US-20020100725-A1 Method for preparing thin fiber-structured polymer web KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-08-01 US claimed
WO-2001006011-A2 ARRAYS COMPRISING NON-COVALENTLY ASSOCIATED NUCLEIC ACID PROBES AND METHODS FOR MAKING AND USING THEM GENOMETRIX GENOMICS, INC. (US) 2001-01-25 WO claimed
EP-0557087-B1 Aqueous aerosol hair-spray compositions with a relatively low content of volatile organic compounds REVLON CONSUMER PROD CORP (US) 1995-12-06 EP claimed
US-5095054-A Molding premixes of a melt of a degraded starch and hydrophobic water-insoluble thermoplastic polymer; dimensional stability; toughness; humidity resistance; receptivity WARNER-LAMBERT COMPANY (US) 1992-03-10 US claimed
EP-0407350-A2 Polymer base blend compositions containing destructurized starch WARNER-LAMBERT COMPANY (US) 1991-01-09 EP claimed
EP-0064388-B1 RETARD ORAL PHARMACEUTICAL COMPOSITIONS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1985-11-06 EP claimed
EP-0064388-A2 Retard oral pharmaceutical compositions CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1982-11-10 EP claimed
US-4108185-A HYDROSOLUBLE POLYMER L'OREAL (FR) 1978-08-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398108-A1 Pharmaceutical Compositions of a Kinase Inhibitor MET, MINK1, PEAK1 OR51E2 3871/4885CRBN 604/4885FKBP5 2404/4885
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients FSCN1, FLNA, PFN1 OR51E2 2939/4885CRBN 3544/4885FKBP5 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.