Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380976 | 0.88 | SLC6A4 (0.49) | SLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL3377985 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL4970732 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL8057378 | 0.72 | MAPT (0.50) | — | |
| SCHEMBL2288493 | 0.71 | SLC6A4 (0.70) | SLC6A4 | |
| SCHEMBL2580468 | 0.71 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL14862428 | 0.71 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL3378696 | 0.69 | SLC6A4 (0.49) | SLC6A4HTR6 | |
| SCHEMBL6110366 | 0.68 | GAA (0.39) | HTR2C | |
| SCHEMBL4450552 | 0.67 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |