Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TCF4 | P15884 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057378 | 0.80 | MAPT (0.50) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL5188701 | 0.77 | MAPT (0.44) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL1010013 | 0.75 | HSP90AA1 (0.41) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4775938 | 0.75 | ALDH1A1 (0.52) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL4748432 | 0.74 | CYP1A2 (0.40) | MAPK1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL7456881 | 0.74 | HPGD (0.50) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL6110366 | 0.73 | GAA (0.39) | ALDH1A1CYP3A4 | |
| SCHEMBL3378693 | 0.72 | SLC6A4 (0.44) | — | |
| SCHEMBL3630701 | 0.72 | FLT1 (0.35) | MAPK1KMT2ANPSR1LMNATDP1 | |
| SCHEMBL4450552 | 0.72 | ALDH1A1 (0.39) | MAPTMAPK1LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881990-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |